Impetigo (cont.)

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What is the treatment for impetigo?

Impetigo is not serious and is very treatable. Mild impetigo can be handled by gentle cleansing, removing crusts, and applying the prescription-strength antibiotic ointment mupirocin (Bactroban). Nonprescription topical antibiotic ointments (such as Neosporin) generally are not effective. More severe or widespread impetigo, especially of bullous impetigo, may require oral antibiotic medication. In recent years, more staph germs have developed resistance to standard antibiotics. Bacterial culture tests can help guide the use of proper oral therapy if needed. Antibiotics which can be helpful include penicillin derivatives (such as Augmentin) and cephalosporins such as cephalexin (Keflex). If clinical suspicion supported by culture results show other bacteria, such as drug-resistant staph (methicillin-resistant Staphylococcus aureus or MRSA), other antibiotics such as clindamycin or trimethoprim-sulfamethoxazole (Bactrim or Septra) may be necessary. Treatment is guided by laboratory results (culture and sensitivity tests).

What are possible complications of impetigo?

One potentially serious, but rare, complication of impetigo caused by strep bacteria is glomerulonephritis, a condition producing kidney inflammation. Many specialists are not convinced that treating impetigo will prevent glomerulonephritis from occurring.

Reviewed by William C. Shiel Jr., MD, FACP, FACR on 6/25/2012

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