IMATINIB - ORAL (Gleevec) side effects, medical uses, and drug interactions.

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GENERIC NAME: IMATINIB - ORAL (ih-MAT-in-ibb)

BRAND NAME(S): Gleevec

USES: Imatinib is used to treat a type of leukemia (chronic myeloid leukemia or CML) as well as certain intestinal tumors (GISTs).

HOW TO USE: Take this medication by mouth with a meal and a large glass of water, usually once or twice daily; or take as directed by your doctor. If you have trouble swallowing the tablets whole, you may dissolve your dose in a glass of water or apple juice. The amount of liquid will vary depending on your dose; consult your doctor or pharmacist for more detailed instructions. Stir the mixture well and drink immediately. The dosage is based on your medical condition and response to therapy.

SIDE EFFECTS: Nausea, vomiting, diarrhea, loss of appetite, dry skin, hair loss, swelling (especially in the legs or around the eyes), or muscle cramps may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: joint/muscle pain, stomach pain, severe weakness. Tell your doctor immediately if any of these unlikely but serious side effects occur: trouble breathing, unusual weight gain, easy bruising or bleeding, persistent sore throat or fever, cold hands/feet. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: yellowing eyes and skin, dark urine, coffee-ground vomit, black stools, one-sided weakness, vision problems, slurred speech, confusion, fast heartbeat. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice any other effects not listed above, contact your doctor or pharmacist.