ibandronate, Boniva

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PREPARATIONS:

  • Tablets: 150 mg
  • Intravenous injection: 3 mg/3 ml

DRUG INTERACTIONS:

  • Calcium supplements, antacids, and other products that contain aluminum, magnesium, or iron may reduce absorption of ibandronate. Ibandronate should be administered at least 60 minutes before administration of any oral medication, including medications containing iron, aluminum, magnesium, or calcium.
  • Patients should wait at least 60 minutes after taking ibandronate before taking other oral medications. The occurrence of irritation in the stomach and intestines may increase if aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), for example, ibuprofen (Motrin), Advil, naproxen (Aleve) are combined with ibandronate.

PREGNANCY AND BREASTFEEDING SAFETY:

  • Bisphosphonates have been shown to cause fetal harm in animals, but there are no data on risk to the fetus in humans. Ibandronate should be used during pregnancy only if the physician feels that its potential benefit justifies the potential risk to the fetus.
  • Ibandronate is secreted into the breast milk of animals. It is not known whether it is secreted into human breast milk. Since most medications do appear in human breast milk, it is generally recommended that caution be exercised when ibandronate is given to women who are nursing.
Medically Reviewed by a Doctor on 6/9/2016

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