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November 24, 2009
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Hypersensitivity Pneumonitis

Revising Medical Author : George Schiffman, MD
Revising Medical Editor: Melissa Conrad Stöppler, MD

What is hypersensitivity pneumonitis and what causes it?

Hypersensitivity pneumonitis is an inflammation of the lung (usually of the very small airways) caused by the body's immune reaction to small air-borne particles. These particles can be bacteria, mold, fungi, or even inorganic matter.

What is acute hypersensitivity pneumonitis?

Acute hypersensitivity pneumonitis tends to occur 4-12 hours after exposure (usually heavy exposure) to the particles.

What are the symptoms of acute hypersensitivity pneumonitis?

Symptoms of acute hypersensitivity pneumonitis include:

  • fever,

  • chills,

  • coughing,

  • shortness of breath,

  • body aches, etc.

Chest x-rays may show diffuse small nodules in the lungs. Typically, the symptoms will subside hours to days after exposure (provided there are no repeated exposures). The Chest x-ray abnormalities will also disappear. The patient's condition can deteriorate after exposure; therefore it is imperative that a medical evaluation be performed to determine the best course of treatment.

What is chronic hypersensitivity pneumonitis?

Chronic (long-term) hypersensitivity pneumonitis causes lung scarring (fibrosis).

What are the symptoms of chronic hypersensitivity pneumonitis?

Symptoms of chronic hypersensitivity pneumonitis include:

  • of shortness of breath and,

  • cough.

Chronic disease is believed to occur after prolonged low grade exposure to the offending particles.



Next: What are examples of hypersensitivity pneumonitis? »

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