hylan G-F 20, Synvisc

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: hylan G-F 20

BRAND NAME: Synvisc, Synvisc-One



USES: Hylan G-F 20 is used for treating pain caused by osteoarthritis of the knee.

SIDE EFFECTS: About 1 in 14 persons experience pain or swelling in the injected knee, and one third of those who do, need to have fluid removed from the knee. Side effects include:

  • injection site pain,
  • injection site stiffness,
  • injection site redness,
  • skin rash,
  • itching,
  • facial flushing and
  • facial swelling.

PREPARATIONS: Injection: 16 mg/2 ml, 48 mg/6 ml

DRUG INTERACTIONS: There are no known drug interactions with hylan G-F 20.

PREGNANCY AND BREASTFEEDING SAFETY: No adequate studies have been done in pregnant women. The risks of hylan G-F 20 during breastfeeding are not known. It is not known if hylan G-F 20 is excreted into breast milk.

Medically Reviewed by a Doctor on 1/15/2016

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