hylan G-F 20, Synvisc

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GENERIC NAME: hylan G-F 20

BRAND NAME: Synvisc, Synvisc-One

DRUG CLASS AND MECHANISM: Hylan G-F 20 is an injectable fluid that is used to treat osteoarthritis of the knee. Osteoarthritis is a type of arthritis in which the joints of the body degenerate and become painful and stiff. Osteoarthritis is the most common form of arthritis; almost 10 million Americans suffer from osteoarthritis. Most affected persons are over 45 years of age, and women are more often affected than men. Joints contain a fluid, called synovial fluid, which acts as a lubricant and shock absorber. Patients with osteoarthritis have synovial fluid that is thinner than normal, and, therefore, it is less effective as a lubricant and shock-absorber. Hylan G-F 20 is an elastic fluid that is made from a substance called hyaluronan, that is found in normal joint fluid. Hyaluronan is the key substance in joint fluid that provides the shock-absorbing quality to the fluid, and it is essential for the proper functioning of joints. When injected into the knee of a patient with osteoarthritis, hylan G-F 20 helps to restore the shock-absorbing effect of the fluid within the knee. This can reduce pain, resulting in a more active lifestyle.

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