- Osteoarthritis Overview Slideshow Pictures
- Osteoarthritis Tips for Living Better Daily Slideshow
- Exercises for OA of the Knee Slideshow
- What is hylan G-F 20 (Synvisc, Synvisc One), and how does it work (mechanism of action)?
- What are the uses for Synvisc?
- What are the side effects of Synvisc?
- Which drugs or supplements interact with Synvisc?
- What's the dosage for Synvisc and Synvisc One, and how is the injection given?
- What brand names are available for hylan G-F 20?
- Do I need a prescription for Synvisc?
- Is this drug safe to take if I'm pregnant or breastfeeding?
- What else should I know about this drug?
What is hylan G-F 20 (Synvisc, Synvisc One), and how does it work (mechanism of action)?
What is hylan G-F 20 (Synvisc, Synvisc One)?
Hylan G-F 20 (Synvisc, Synvisc One) is an injectable fluid that is used to treat osteoarthritis (OA) of the knee. Osteoarthritis is a type of arthritis in which the joints of the body degenerate and become painful and stiff. Osteoarthritis is the most common form of arthritis. Almost 10 million Americans suffer from the disease. Most people with OA are those 45 years old, and women. More women have OA than men.
How does Synvisc work?
Joints contain a fluid, called synovial fluid, which acts as a lubricant and shock absorber. Patients with osteoarthritis have synovial fluid that is thinner than normal, and, therefore, it is less effective as a lubricant and shock-absorber. Synvisc is an elastic fluid that is made from a substance called hyaluronan, that is found in normal joint fluid. Hyaluronan is the key substance in joint fluid that provides the shock-absorbing quality to the fluid, and it is essential for the proper functioning of joints. When Synvisc is injected into the knee of a patient with osteoarthritis, the drug helps to restore the shock-absorbing effect of the fluid within the knee. This can reduce pain, resulting in a more active lifestyle.
What are the uses for Synvisc?
Synvisc is used for treating pain caused by osteoarthritis of the knee.
What are the side effects of Synvisc?
About 1 in 14 persons experience pain or swelling in the injected knee, and one third of those who do, need to have fluid removed from the knee.
Common side effects include:
Other side effects include:
- Injection site pain
- Injection site stiffness
- Injection site redness
- Skin rash
- Facial flushing
- Facial swelling
Which drugs or supplements interact with Synvisc?
There are no known drug interactions with Sinvisc.
Quick GuideOsteoarthritis (OA): Treatment, Symptoms, Diagnosis
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