hydroxyurea (Hydrea, Droxia)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Is hydroxyurea-oral safe to take if I'm pregnant or breastfeeding?

Hydroxyurea can cause harm to the unborn baby and therefore, should not be used during pregnancy. Although there are no adequate and well-controlled studies in pregnant women, in animals studies hydroxyurea was found to cause birth defects.

Hydroxyurea is secreted in human milk. Nursing should be stopped due to the potential for serious adverse reactions in the infant.

What else should I know about hydroxyurea-oral?

What preparations of hydroxyurea-oral are available?

  • Hydrea: 500 mg capsules. Hydrea is used an antineoplastic agent.
  • Droxia: 200 mg, 300 mg, 400 mg capsules. Droxia is used to treat sickle cell disease.

How should I keep hydroxyurea-oral stored?

Capsules should be stored at room temperature between 59 F to 86 F (15 C to 30 C).

REFERENCE: FDA Prescribing Information.

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