hydroxyurea (Hydrea, Droxia)

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GENERIC NAME: hydroxyurea

BRAND NAME: Hydrea, Droxia

DRUG CLASS AND MECHANISM: Hydroxyurea (Hydrea) is an oral medication used to treat several types of cancers including chronic myelogenous leukemia (CML), acute myelogenous leukemia (AML), head and neck cancer, malignant melanoma, ovarian cancer, and polycythemia vera (a disorder of the bone marrow). The exact mechanism by which hydroxyurea works to treat cancer is not understood. However, it is thought that hydroxyurea causes an immediate inhibition of DNA synthesis by inhibiting an enzyme called ribonucleotide reductase. Interrupting DNA synthesis reduces the growth of cancer cells.

Medically Reviewed by a Doctor on 6/9/2015

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