hydrocortisone oral, Hydrocortone, Cortef (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Hydrocortisone impairs calcium absorption and new bone formation. Patients on prolonged treatment with hydrocortisone and other corticosteroids can develop osteoporosis and an increased risk of bone fractures. Supplemental calcium and vitamin D are encouraged to slow this process of bone thinning.

In rare individuals, destruction of large joints (aseptic necrosis) can occur while undergoing treatment with hydrocortisone or other corticosteroids. These patients experience severe pain in the joints involved, and can require joint replacements. The reason behind such destruction is not clear.

Reference: FDA Prescribing Information


Last Editorial Review: 2/3/2012



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