hydrocortisone rectal foam (Cortifoam, Anusol-HC, Anucort-HC)

  • Pharmacy Author:
    Eni Williams, PharmD, PhD

    Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What is hydrocortisone-rectal foam, and how does it work (mechanism of action)?

Hydrocortisone is a natural corticosteroid produced by the adrenal glands that are located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory conditions of the nose and eyes. There are numerous preparations of corticosteroids including oral tablets, capsules, liquids, topical creams and gels, inhalers and eye drops, as well as injectable and intravenous solutions. Hydrocortisone that is used for rectal conditions is discussed in this article. The FDA approved hydrocortisone in December 1952.

What brand names are available for hydrocortisone-rectal foam?

Cortifoam, Anusol-HC, Anucort-HC, Proctocort, Colocort, Cortenema, Hemmorex-HC

Is hydrocortisone-rectal foam available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for hydrocortisone-rectal foam?

Yes

What are the uses for hydrocortisone-rectal foam?

Hydrocortisone is used rectally for the treatment of ulcerative proctitis, inflamed hemorrhoids, and anal itching, burning, and inflammation caused by several conditions that affect the anal area.

What are the side effects of hydrocortisone-rectal foam?

Hydrocortisone's most common side effects when applied to the rectum include:

Other side effects include:

  • local pain and
  • rectal bleeding

What is the dosage for hydrocortisone-rectal foam?

For proctitis the usual dosage is one suppository applied in the morning and night time. Severe cases may require application 3 times daily or 2 suppositories twice daily. One enema is applied at bedtime for 21 days or until symptoms resolve. The dosing for foam is one applicator once daily or every 12 hours for 2-3 weeks, then every other day if necessary.

Which drugs or supplements interact with hydrocortisone-rectal foam?

The risk of drug interactions is low when hydrocortisone is administered rectally.

What else should I know about hydrocortisone-rectal foam?

What preparations of hydrocortisone-rectal foam are available?

Enema: 100 mg/60 ml; Foam: 10% (15 g); Suppository: 25 and 30 mg

How should I keep hydrocortisone-rectal foam stored?

Hydrocortisone should be store at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container.

Medically reviewed by John Cunha, DO

REFERENCE: FDA Prescribing Information.

Last Editorial Review: 8/8/2017

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Reviewed on 8/8/2017
References
Medically reviewed by John Cunha, DO

REFERENCE: FDA Prescribing Information.

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