hydrocortisone, rectal suppository, enema, foam, Cortifoam, Anusol-HC, Anucort-HC, Proctocort (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Hydrocortisone is used rectally for the treatment of ulcerative proctitis, inflamed hemorrhoids, and anal itching, burning, and inflammation caused by several conditions that affect the anal area.

SIDE EFFECTS: Hydrocortisone's side effects when applied to the rectum include:



PREPARATIONS: Enema: 100 mg/60 ml; Foam: 10% (15 g); Suppository: 25 and 30 mg

STORAGE: Hydrocortisone should be store at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container.


  • For proctitis the usual dosage is one suppository applied in the morning and night time.
  • Severe cases may require application 3 times daily or 2 suppositories twice daily.
  • One enema is applied at bedtime for 21 days or until symptoms resolve.
  • The dosing for foam is one applicator once daily or every 12 hours for 2-3 weeks, then every other day if necessary.

DRUG INTERACTIONS: The risk of drug interactions is low when hydrocortisone is administered rectally.

PREGNANCY: Hydrocortisone has not been adequately evaluated during pregnancy.

NURSING MOTHERS: Hydrocortisone taken orally can appear in breast milk, and can have adverse effects on the baby. It is not known whether hydrocortisone administered rectally is absorbed in sufficient amounts to appear in breast milk.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 1/29/2015

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