hydrocortisone, rectal suppository, enema, foam, Cortifoam, Anusol-HC, Anucort-HC, Proctocort

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Enema: 100 mg/60 ml; Foam: 10% (15 g); Suppository: 25 and 30 mg

STORAGE: Hydrocortisone should be store at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container.

DOSING:

  • For proctitis the usual dosage is one suppository applied in the morning and night time.
  • Severe cases may require application 3 times daily or 2 suppositories twice daily.
  • One enema is applied at bedtime for 21 days or until symptoms resolve.
  • The dosing for foam is one applicator once daily or every 12 hours for 2-3 weeks, then every other day if necessary.

DRUG INTERACTIONS: The risk of drug interactions is low when hydrocortisone is administered rectally.

PREGNANCY: Hydrocortisone has not been adequately evaluated during pregnancy.

NURSING MOTHERS: Hydrocortisone taken orally can appear in breast milk, and can have adverse effects on the baby. It is not known whether hydrocortisone administered rectally is absorbed in sufficient amounts to appear in breast milk.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 1/29/2015
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