hydrocodone/acetaminophen, Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, No

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GENERIC NAME: hydrocodone/acetaminophen

BRAND NAMES: Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, Norco, Zydone

DRUG CLASS AND MECHANISM: Hydrocodone is a narcotic pain-reliever and a cough suppressant, similar to codeine. Hydrocodone blocks the receptors on nerve cells in the brain that give rise to the sensation of pain. Acetaminophen is a non-narcotic analgesic (pain reliever) and antipyretic (fever reducer). Acetaminophen works by elevating the threshold to pain, that is, in order for pain to be felt, greater stimulation of the nerves responsible for the sensation of pain is necessary. It reduces fever through its action on the temperature-regulating center of the brain. Frequently, hydrocodone and acetaminophen are combined to achieve pain relief, as in Vicodin and Lortab. The FDA approved Vicodin in January 1983.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets, capsules and liquid. Among the many brands the dose of acetaminophen ranges between 300 and 750 mg, and the dose of hydrocodone ranges between 2.5 and 10 mg.

Vicodin was recently reformulated, and the acetaminophen component was reduced to 300 mg in all preparations, however, generic formulations may still contain 500 and 750 mg of acetaminophen.

Medically Reviewed by a Doctor on 12/11/2013



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