hydrocodone/homatropine (Hycodan [discontinued] Tussigon) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Homatropine can increase pressure inside the eye and this is dangerous for those with glaucoma.

PREPARATIONS: Tablet: 5 mg /1.5 mg

DRUG INTERACTIONS: Combining alcohol and other sedatives with hydrocodone can lead to increased sedation and even cause confusion. Hydrocodone should not be taken with any of the monoamine oxidase inhibitor (MAOI) class of antidepressants, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl), and procarbazine (Matulane) or other drugs that inhibit monoamine oxidase, for example, linezolid (Zyvox). Such combinations may lead to confusion, high blood pressure, tremor, hyperactivity, coma, and death.

Hydrocodone should not be administered within 14 days of stopping an MAOI.

PREGNANCY AND BREASTFEEDING SAFETY: There are no adequate studies of hydrocodone in pregnant women. Hydrocodone is excreted in breast milk, and, therefore, should be used cautiously by nursing mothers.

STORAGE: Hydrocodone/homatropine should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).

DOSING:

  • The dose for adults and children older than 12 years is one tablet (5 mg/1.5 mg) orally every 4 to 6 hours. The maximum dose is 30 mg/9 mg (6 tablets) in 24 hours.
  • Children 6 to 12 years of age receive a 1/2 tablet (2.5 mg/0.75 mg) every 4 to 6 hours not to exceed 3 tablets (15 mg/4.5 mg)
Medically Reviewed by a Doctor on 1/15/2016


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