hydrocodone/homatropine - oral, Hycodan, Tussigon

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GENERIC NAME: hydrocodone/homatropine

BRAND NAMES: Tussigon; Hycodan (discontinued in US)

DRUG CLASS AND MECHANISM: Hydrocodone is an opioid narcotic pain-reliever cough suppressant that is similar to codeine, oxycodone, morphine, methadone, fentanyl, and other opioids. Hydrocodone, like other opioids, stimulates receptors on nerves in the brain to increase the threshold to pain (the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). It also works directly on the cough center in the brain to reduce cough.

Homatropine blocks the action of acetylcholine, a chemical (neurotransmitter) that nerves use to communicate. It is added in low doses to discourage deliberate overdoses of hydrocodone. The FDA approved hydrocodone/homatropine in July 1985.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablet: 5 mg /1.5 mg

STORAGE: Hydrocodone/homatropine should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Hydrocodone/homatropine is prescribed for the treatment of cough in adults and in children 6 years of age and older.

DOSING: The dose for adults and children older than 12 years is one tablet (5 mg/1.5 mg) orally every 4 to 6 hours. The maximum dose is 30 mg/9 mg (6 tablets) in 24 hours. Children 6 to 12 years of age receive a 1/2 tablet (2.5 mg/0.75 mg) every 4 to 6 hours not to exceed 3 tablets (15 mg/4.5 mg)

Medically Reviewed by a Doctor on 4/16/2014



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