hydrocodone/homatropine (Hycodan [discontinued] Tussigon)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: hydrocodone/homatropine

BRAND NAMES: Tussigon

DISCONTINUED BRANDS: Hycodan

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Hydrocodone/homatropine is prescribed for the treatment of cough in adults and in children 6 years of age and older.

SIDE EFFECTS: The most common side effects of hydrocodone are:

Other important side effects include

  • drowsiness,
  • constipation,
  • spasm of the ureter, and
  • difficulty in urinating.

Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery. Hydrocodone can depress breathing, and should be used with caution in elderly, debilitated patients and in patients with serious lung disease. Hydrocodone is habit forming. Mental and physical dependence can occur when used long-term.

Homatropine can increase pressure inside the eye and this is dangerous for those with glaucoma.

PREPARATIONS: Tablet: 5 mg /1.5 mg

DRUG INTERACTIONS: Combining alcohol and other sedatives with hydrocodone can lead to increased sedation and even cause confusion. Hydrocodone should not be taken with any of the monoamine oxidase inhibitor (MAOI) class of antidepressants, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl), and procarbazine (Matulane) or other drugs that inhibit monoamine oxidase, for example, linezolid (Zyvox). Such combinations may lead to confusion, high blood pressure, tremor, hyperactivity, coma, and death.

Medically Reviewed by a Doctor on 1/15/2016
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