- Surprising Reasons You're in Pain Slideshow
- Take the Pain Quiz
- Joint-Friendly Exercises to Reduce RA Pain Slideshow
- What is hydrocodone and ibuprofen, and how does it work (mechanism of action)?
- What brand names are available for hydrocodone and ibuprofen?
- Is hydrocodone and ibuprofen available as a generic drug?
- Do I need a prescription for hydrocodone and ibuprofen?
- What are the side effects of hydrocodone and ibuprofen?
- What is the dosage for hydrocodone and ibuprofen?
- Which drugs or supplements interact with hydrocodone and ibuprofen?
- Is hydrocodone and ibuprofen safe to take if I'm pregnant or breastfeeding?
- What else should I know about hydrocodone and ibuprofen?
What is hydrocodone and ibuprofen, and how does it work (mechanism of action)?
Vicoprofen is a combination of an opioid analgesic (hydrocodone bitartrate, a pain reliever related to narcotics) and a nonsteroidal anti-inflammatory drug (ibuprofen). Both medications are effective for pain management. It is estimated that one tablet of Vicoprofen is as effective as two tablets of Tylenol #3 (acetaminophen 300 mg plus codeine 30 mg). Vicoprofen was approved by the FDA in 1997.
What brand names are available for hydrocodone and ibuprofen?
Vicoprofen, Reprexain, Xylon
Is hydrocodone and ibuprofen available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for hydrocodone and ibuprofen?
What are the side effects of hydrocodone and ibuprofen?
The most frequent side effects experienced with hydrocodone include:
- dyspepsia (indigestion),
- anxiety, nervousness, and somnolence (drowsiness).
Other important side effects include constipation and spasm of the ureter, which can lead to difficulty inurinating.
The most common side effects of ibuprofen involve the gastrointestinal system. It can cause ulcerations, abdominal pain, cramping, nausea, gastritis, and even serious gastrointestinal bleeding. Sometimes, stomach ulceration and bleeding can occur without abdominal pain, and black tarry stools, weakness, and dizziness upon standing may be the only signs of internal bleeding. Rash, kidney impairment, ringing in the ears (tinnitus), and lightheadedness can also occur.
Hydrocodone can depress breathing, and is used with caution in the elderly, debilitated patients and those with a history of ulcer or serious lung disease. Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery. Hydrocodone may be habit forming. Mental and physical dependence can occur but are unlikely when used for short-term pain relief.
Quick GuideChronic Pain: Causes and Solutions
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.