PRECAUTIONS: Before you take this medication tell your doctor if you have: diabetes, kidney or liver disease, any drug allergies. Caution must be observed when eating large amounts of food high in potassium such as bananas, baked potatoes, cantaloupe, avocado, raisins, cooked spinach and other foods. Consult your doctor or nutritionist. Alcoholic beverages may increase the effects of this drug, causing dizziness or lightheadedness. Limit alcohol intake. Use caution engaging in activities requiring alertness. Because this drug changes your fluid balance, you may feel dizzy if you change from a lying to a standing position too rapidly. Avoid this by sitting up a few minutes before rising. If an illness causes severe vomiting or diarrhea, the fluid balance in your body can be upset; contact your doctor. Unlike other diuretics, amiloride does not cause potassium loss from the body. Do not use salt substitutes without your doctor's permission. Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects of the drug. Tell your doctor if you are pregnant before using this drug. One of the components of this drug passes into breast milk. Some doctors recommend avoiding the use of hydrochlorothiazide for the first month of breast-feeding because it may decrease milk output. Consult your doctor before nursing.

DRUG INTERACTIONS: This drug is not recommended for use with: dofetilide. Ask your doctor or pharmacist for more details. Tell your doctor of any over-the-counter or prescription drugs you are taking, especially of: ACE Inhibitors (e.g., captopril, lisinopril), Angiotensin receptor blockers (ARBs such as losartan, valsartan), digoxin, lithium, triamterene, spironolactone, potassium supplements, medication for arthritis, diabetes medications, high blood pressure drugs. Do not start or stop any medicine without doctor or pharmacist approval.