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February 9, 2010
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Medications and Drugs

GENERIC NAME: HYDROCHLOROTHIAZIDE - ORAL (HI-dro-klor-oh-THIGH-uh-zide)

BRAND NAME(S): Microzide

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: Hydrochlorothiazide is a "water pill" (diuretic) that increases the amount of urine you make, which causes your body to get rid of excess water. This drug is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication also reduces swelling/fluid retention (edema) which can result from conditions such as congestive heart failure, liver disease, or kidney disease. This can help to improve symptoms such as trouble breathing.

OTHER USES: This medication may also be used for a condition known as "water diabetes" (diabetes insipidus) and to help prevent calcium kidney stones.

HOW TO USE: Take this medication by mouth with or without food, as directed by your doctor. The dosage is based on your medical condition and response to therapy. It is best to take this medication early in the day, before 4-6PM, to prevent having to wake up during the night to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) of the day as directed. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Do not stop taking this medication without consulting your doctor. Cholestyramine and colestipol can decrease the absorption of hydrochlorothiazide. If you are taking either of these drugs, separate hydrochlorothiazide from cholestyramine by at least 4 hours and from colestipol by at least 2 hours. If your condition persists or worsens, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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  • Drug Interactions - Learn about potential drug interactions you may be exposed to. Drug interactions can occur with prescription drugs, OTC medication, vitamins, herbs, and supplements.
  • Electrolytes - Read about blood electrolytes (sodium, potassium, chloride, and bicorbonate) and the effects of electrolyte imbalances like kidney failure, low blood pressure, hypokalemia, and hyperkalemia.
  • Kidney Failure - Learn about kidney failure, in which the body has fluid retention, risen blood pressure, toxin build up and lack of red blood cells. Symptoms include fatigue, nausea, and apetite loss.

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