hydralazine/hydrochlorothiazide - oral, Apresazide (cont.)
USES: This medication contains 2 drugs (hydralazine and hydrochlorothiazide) and is used to treat high blood pressure. Hydralazine is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily. Hydrochlorothiazide is a "water pill" (diuretic). It works by increasing the amount of urine that you make. This effect causes your body to get rid of extra salt and water, which probably also helps relax the blood vessels. These 2 drugs are used together when 1 medication is not controlling your blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
HOW TO USE: Take this medication by mouth with or without food, usually twice daily or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule.Cholestyramine and colestipol can decrease the absorption of this medication. If you are taking either of these drugs, take them at least 4 hours apart from this medication.The dosage is based on your age, medical condition, and response to treatment. Your doctor may start you at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to several weeks before you get the full benefit of this drug.Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.Tell your doctor if your condition worsens (for example, your routine blood pressure readings increase).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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