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February 8, 2012
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hydralazine/hydrochlorothiazide - oral, Apresazide

GENERIC NAME: HYDRALAZINE/HYDROCHLOROTHIAZIDE - ORAL (hye-DRAL-a-zeen/HYE-droe-KLOR-oh-THYE-a-zide)

BRAND NAME(S): Apresazide

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: This product contains 2 drugs (hydralazine and hydrochlorothiazide). Generally, it should not be used when treating high blood pressure for the first time. Your doctor should first give you each of the drugs separately so that he or she can find the best dose of each drug for you. Use this combination product only if your doctor has decided that the doses of each drug in this product are right for your condition. Your doctor may need to continually adjust your medications depending on your condition.

USES: This medication contains 2 drugs (hydralazine and hydrochlorothiazide) and is used to treat high blood pressure. Hydralazine is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily. Hydrochlorothiazide is a "water pill" (diuretic). It works by increasing the amount of urine that you make. This effect causes your body to get rid of extra salt and water, which probably also helps relax the blood vessels. These 2 drugs are used together when 1 medication is not controlling your blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

HOW TO USE: Take this medication by mouth with or without food, usually twice daily or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule.Cholestyramine and colestipol can decrease the absorption of this medication. If you are taking either of these drugs, take them at least 4 hours apart from this medication.The dosage is based on your age, medical condition, and response to treatment. Your doctor may start you at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to several weeks before you get the full benefit of this drug.Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.Tell your doctor if your condition worsens (for example, your routine blood pressure readings increase).




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      • Night sweats are severe hot flashes that occur at night and result in a drenching sweat. In order to distinguish night sweats that arise from medical causes from those that occur because one's surroundings are too warm, doctors generally refer to true night sweats as severe hot flashes occurring at night that can drench sleepwear and sheets, which are not related to an overheated environment.
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hydralazine/hydrochlorothiazide - oral, Apresazide

Introduction

Doctors in primary care fields of medicine often hear their patients complain of night sweats as they are common. Night sweats refer to any excess sweating occurring during the night. However, if your bedroom is unusually hot or you are using too many bedclothes, you may begin to sweat during sleep - and this is normal. In order to distinguish night sweats that arise from medical causes from those that occur because one's surroundings are too warm, doctors generally refer to true night sweats as severe hot flashes occurring at night that can drench sleepwear and sheets, which are not related to an overheated environment.

In one study of 2267 patients visiting a primary care physician, 41% reported experiencing night sweats during the previous month, so the perception of excessive sweating at night is fairly common. It is important to note that flushing (a warmth and redness of the face or trunk) may also be hard to distinguish ...

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