hyaluronate (hyaluronan, Hyalgan, Supartz, Euflexxa, Orthovisc)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Solution for injection into the knee joint (intra-articular injection): 10 mg/ml or 15 mg/ml

STORAGE: Sodium hyaluronate should be stored in the original packaging below 25 C (77 F). It should be protected from light.

DOSING: Sodium hyaluronate is administered into the knee joint (intra-articular injection) once a week for a total of 3-5 injections. 20 mg (Euflexxa, Hyalgan) or 25 mg (Supartz) should be injected into the affected knee once weekly.

DRUG INTERACTIONS: No clinically significant drug-drug interactions between sodium hyaluronate injection and other medications have been reported.

PREGNANCY: It is not known whether sodium hyaluronate is safe to use during pregnancy because it has not been evaluated in pregnant women.

NURSING MOTHERS: It is not known if sodium hyaluronate can enter human milk. The safety and effectiveness of sodium hyaluronate has not been established in nursing mothers.

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 10/14/2015

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