- Osteoarthritis Overview Slideshow Pictures
- Osteoarthritis Tips for Living Better Daily Slideshow
- Exercises for OA of the Knee Slideshow
- What is hyaluronate-injection, and how does it work (mechanism of action)?
- What brand names are available for hyaluronate-injection?
- Is hyaluronate-injection available as a generic drug?
- Do I need a prescription for hyaluronate-injection?
- What are the side effects of hyaluronate-injection?
- What is the dosage for hyaluronate-injection?
- Which drugs or supplements interact with hyaluronate-injection?
- Is hyaluronate-injection safe to take if I'm pregnant or breastfeeding?
- What else should I know about hyaluronate-injection?
What is hyaluronate-injection, and how does it work (mechanism of action)?
Hyaluronic acid is a natural chemical that is found in almost all species of animal and in various parts of the human body. It works as a biological lubricant, reducing friction between adjacent tissues. It is present in high amounts in joints and synovial fluid (the fluid that fills the knee joint).
Sodium hyaluronate is used for the treatment of pain due to osteoarthritis of the knee in patients who do not get adequate relief from simple pain medicines or from exercise and physical therapy. It is administered by injection directly into the knee joint (intra-articular injection).
The exact mechanism by which sodium hyaluronate products work is not known. The synovial fluid in the knees helps lubricate and cushion our joints during movement. Sodium hyaluronate is the major component in the synovial fluid. People with osteoarthritis do not have enough hyaluronic acid in their synovial fluid. It is thought that sodium hyaluronate injection helps restore synovial fluid, thereby reducing some of the pain and discomfort associated with osteoarthritis.
The first sodium hyaluronate injection was approved in the US in 1997.
What brand names are available for hyaluronate-injection?
Hyalgan, Supartz, Euflexxa, Orthovisc
Is hyaluronate-injection available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for hyaluronate-injection?
What are the side effects of hyaluronate-injection?
Common side effects include:
- Pain at the injection site
- Swelling of the knee
- Upset stomach
Other reported side effects include:
- Increased blood pressure
- Feeling sick
Quick GuideOsteoarthritis (OA): Treatment, Symptoms, Diagnosis
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