Hops

Are there any interactions with medications?



Alcohol
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Alcohol can cause sleepiness and drowsiness. Hops might also cause sleepiness and drowsiness. Taking large amounts of hops along with alcohol might cause too much sleepiness.



Estrogens
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Hops might have some of the same effects as estrogen. Taking hops along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.



Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Hops might decrease how quickly the liver breaks down some medications. Taking hops along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking hops, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include chlorzoxazone, theophylline, and bufuralol.



Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Hops might decrease how quickly the liver breaks down some medications. Taking hops along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking hops, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), and others.



Medications changed by the liver (Cytochrome P450 1B1 (CYP1B1) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Hops might decrease how quickly the liver breaks down some medications. Taking hops along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking hops, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include theophylline, omeprazole, clozapine, progesterone, lansoprazole, flutamide, oxaliplatin, erlotinib, and caffeine.



Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Hops might decrease how quickly the liver breaks down some medications. Taking hops along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking hops, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Versed), and others.



Sedative medications (CNS depressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Hops might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking hops along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Dosing considerations for Hops.

The appropriate dose of hops depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for hops. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.


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