Historically, Ilex opaca fruit tea was used as a heart stimulant by American Indians. Ilex vomitoria was used to cause vomiting, and Yaupon tea (mixed leaves of Ilex cassine, Ilex vomitoria, and Ilex dahoon) was used as a ceremonial "cleanser" in South America.
More recently, preparations of holly leaf have been used for coughs, digestive disorders, water retention, and yellowed skin (jaundice). Ilex aquifolium leaves are used for treating fevers that come and go, joint pain (rheumatism), swelling, water retention, and chest congestion. Ilex opaca leaves are used to empty and cleanse the bowels, stimulate the heart, and increase urine flow. Other holly species are used for treating heart disease, dizziness, and high blood pressure.
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