MedicineNet.com

About Us | Privacy Policy | Site Map
February 7, 2012
Font Size
A
A
A

Hives
(Urticaria & Angioedema)

Medical Author:
Medical Author:
Medical Editor:
Doctor to Patient

Are Hives Always Caused by an Allergy?

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

Read about the causes, symptoms, and treatment of hives.Hives are swollen, red or pink bumps, patches, or welts on the skin that usually appear suddenly. Itching is the most common symptom associated with hives, although some people report that hives cause a stinging or burning sensation. Hives are a very common reaction to all kinds of stimuli. While an allergic reaction can be a cause of hives, in the majority of outbreaks, the exact cause of hives is not known. Hives are also known as urticaria.

Hives form when a chemical called histamine is released by specialized cells known as mast cells. It is true that allergic reactions ultimately lead to the release of histamine, but other circumstances can result in the release of histamine, causing an outbreak of hives. Histamine acts by causing blood vessels to leak fluid into the nearby tissues. In the skin, small areas of swelling develop as a result of capillary (the smallest blood vessels) leakage.

In addition to allergic reactions to medications, foods, or other substances, hives may be triggered by direct physical stimulation such as temperature extremes, water, sun, and physical exercise. Having a viral infection can also cause an outbreak of hives, and even stress and nervousness have been associated with hives outbreaks. In the form of hives known as dermographia, or "skin writing," raised, itchy red welts with adjacent flares appear wherever the skin is scratched or where belts and other articles of clothing rub against the skin.


Doctor to Patient

What are hives (urticaria) and angioedema?

Hives (medically known as urticaria) appear on the skin as wheals which are red, very itchy, smoothly elevated areas of skin often with a blanched center. They appear in varying shapes and sizes, from a few millimeters to several inches in diameter anywhere on the body.

It is estimated that 20% of all people will develop urticaria at some point in their lives. Hives are more common in women than in men. One hallmark of hives is their tendency to change size rapidly and to move around, disappearing in one place and reappearing in other places, often in a matter of hours. Individual hives usually last no longer than 24 hours. An outbreak that looks impressive, even alarming, first thing in the morning can be completely gone by noon, only to be back in full force later in the day. Very few, if any other skin diseases occur and then resolve so rapidly. Therefore, even if you have no evidence of hives to show the doctor when you get to the office for examination, he or she can often establish the diagnosis based upon the history of your symptoms. Because hives fluctuate so much and so fast, it is helpful to bring along a photograph of what the outbreak looked like at its worst.

Swelling deeper in the skin that may accompany hives is called angioedema. This swelling may be seen on the hands and feet, as well as the lips or eyes, that can be as dramatic as it is brief.

What causes hives and angioedema?

Hives are produced when histamine and other compounds are released from cells called mast cells, which are normally found in the skin. Histamine causes fluid to leak from the local blood vessels, leading to swelling in the skin.

Hives are very common. Although they can be annoying, they usually resolve on their own over a period of weeks and are rarely medically serious. Some hives are caused by allergies to such things as foods, medications, and insect stings, but in the majority of cases, no specific cause for them is ever found. Although patients may find it frustrating not to know what has caused their hives, maneuvers like changing diet, soap, detergent, and makeup are hardly ever helpful in preventing hives and are not necessary for the most part.

Having hives may cause stress, but stress by itself does not cause hives.

In rare cases (some hereditary, others caused by bee stings or drug allergy), urticaria and angioedema are accompanied by a striking decrease in blood pressure (shock) and difficulty breathing. This is called anaphylaxis. Ordinary hives may be widespread and disturbing to look at, but the vast majority of cases of hives do not lead to life-threatening complications.

Pictures of hives
What does urticaria (hives) look like?


Patient Discussions

Viewers share their comments

Hives - Treatments Question: How did you treat your hives?
Hives - Treatment Question: What was your treatment for hives?
Hives - Describe Your Experience Question: Please describe your experience with hives.

MedicineNet Doctors

Suggested Reading on Hives by Our Doctors

  • Related Diseases & Conditions

    • Rash
      • The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
    • Eczema
      • Eczema, also known as dermatitis, is a general term for many types of skin inflammation. The most common form of eczema is atopic dermatitis. The other forms of eczema include: contact eczema, seborrheic eczema, Nummular eczema, Neurodermatitis, stasis dermatitis, and dyshidrotic eczema. Symptoms, diagnosis, and treatment of eczema may vary from person to person and may depend on the type of eczema.
    • Itching
      • Itching can be a common problem. Itches can be localized or generalized. There are many causes of itching to include: infection (jock itch, vaginal itch), disease (hyperthyroidism, liver or kidney), reactions to drugs, and skin infestations (pubic or body lice). Treatment for itching varies depending on the cause of the itch.
    • Atopic Dermatitis
      • Eczema is a general term for many types dermatitis (skin inflammation). Atopic dermatitis is the most common of the many types of eczema. Other types of eczema include: contact eczema, allergic contact eczema, seborrheic eczema, nummular eczema, stasis dermatitis, and. dyshidrotic eczema.
    • Food Allergy
      • The most common food allergies are to eggs, nuts, milk, peanuts, fish, shellfish, strawberries and tomatoes. Symptoms and signs include nausea, vomiting, diarrhea, abdominal pain, itching, hives, eczema, asthma, lightheadedness, and anaphylaxis. Allergy skin tests, RAST, and ELISA tests may be used to diagnose a food allergy. Though dietary avoidance may be sufficient treatment for mild allergies, the use of an Epipen may be necessary for severe food allergies.
    • Allergy
      • An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
    • Anaphylaxis
      • Anaphylaxis is a serious allergic reaction that affects a number of different areas of the body at one time, and can be fatal. Causes of anaphylaxis can be food allergy, latex allergy, allergy to insect or but stings/bites, asthma, or other materials or conditions. Symptoms include flushing, itching, hives, anxiety, rapid or irregular pulse. Severe symptoms may be throat and tongue swelling, swallowing, and difficulty breathing. Some disorders appear similar to anaphylaxis such as fainting, panic attacks, blood clots in the lungs, heart attacks, and septic shock. If you think that you may be having an anaphylactic reaction, seek emergency care or call 911 immedately.
    • Black Eye
      • The most common cause of a black eye is due to an injury to the face or head. Most black eye injuries are minor and heal on their own, however, some may lead to significant injury. In addition to trauma to the face, cosmetic surgery can cause a black eye(s) as a side effect. People should be aware of the situations in which medical care should be sought immediately for a black eye.
    • Bug Bites and Stings
      • Bug bites and stings have been known to transmit insect-borne illnesses such as West Nile virus, Rocky Mountain spotted fever, and Lyme disease. Though most reactions to insect bites and stings are mild, some reactions may be life-threatening. Preventing bug bites and stings with insect repellant, wearing the proper protective attire, and not wearing heavily scented perfumes when in grassy, wooded, and brushy areas is key.
    • Drug Allergies
      • Drug allergies are cause when the immune system mistakenly creates an immune response to a medication. Symptoms of a drug allergic reaction include hives, rash, itchy skin or eyes, dizziness, nausea, diarrhea, fainting and anxiety. The most common drug allergy is penicillin. Treatment may involve antihistamines or corticosteroids. An Epipen may be used for life-threatening anaphylactic symptoms.
  • Medications

  • Procedures & Tests

  • Pictures, Images & Illustrations

  • Doctor's & Expert's Views

  • Health News

  • Health Features

Women's Health

Find out what women really need.



Symptom Checker: Your Guide to Symptoms & Signs: Pinpoint Your Pain



Hives

How Often Are Allergy Shots Given?

Allergy shots are given regularly (in the upper arm), with gradually increasing doses. When starting immunotherapy, you will need to go to your healthcare provider once or twice a week for several months. The dose is increased each time until the maintenance dose is reached. If the shots are effective, you will go to your healthcare provider every 2 to 4 weeks for 2 to 5 more years. You may become less sensitive to allergens during this time, and your allergy symptoms will become milder and may even go away completely.

How Should I Prepare for Allergy Shots?

For two hours before and after your appointment, do not exercise or engage in vigorous activity. Exercise may stimulate increased blood flow to the tissues and promote faster release of antigens into the bloodstream.

Tell your doctor about all the medications you are taking. Some medications, such as beta blockers, can int...

Read the Allergy Shots article »







Use Pill Finder Find it Now

Pill Identifier on RxList

  • quick,
    easy,
    pill identification

Find a Local Pharmacy

  • including
    24 hour
    pharmacies