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February 10, 2012

Histoplasmosis

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Histoplasmosis Symptoms

What are the symptoms of histoplasmosis?

Most infected persons have no apparent ill effects. The acute respiratory disease is characterized by respiratory symptoms, a general ill feeling, fever, chest pains, and a dry or nonproductive cough. Distinct patterns may be seen on a chest x-ray. Chronic lung disease resembles tuberculosis and can worsen over months or years. The disseminated form is fatal unless treated.

SOURCE: CDC


What is histoplasmosis?

Histoplasmosis is a disease, usually affecting the lungs, caused by the Histoplasma capsulatum fungus. Although many people that are or have been infected with H. capsulatum do not appear ill, some people in the acute phase of the disease have a dry cough, fever, and chest pains and do feel ill. There are several types of histoplasmosis (acute, chronic, and disseminated, all with subtypes).

H. capsulatum was first described by Samuel Darling in 1906 within human tissue cells (histiocytes). In 1932, Katharine Dodd and Edna Tompkins made the first diagnosis of histoplasmosis in an infant. Since the 1930s, H. capsulatum has been found worldwide, but the majority of cases are found in river valleys in temperate regions of the world and in equatorial Africa (in Africa, H. capsulatum has a variant thick-walled yeast form termed H. duboisii). Often an outbreak occurs in a group of people after a visit to a certain area like a cave that contains bat droppings. In the U.S., histoplasmosis is endemic in the Ohio, Missouri, and Mississippi river valleys.

Histoplasmosis is the most common endemic fungal infection diagnosed in the U.S. with about 250,000 new cases per year. H. capsulatum can occur in high concentrations in some sources (for example, bird and bat feces). Histoplasmosis has also been named Ohio River Valley fever and bird-fancier's disease. Histoplasmosis can affect other mammals like dogs and cats, but these animals do not transfer the disease to humans or to other animals. Dogs, cats, and other mammals develop symptoms mainly due to lung infections with H. capsulatum that mimic human histoplasmosis.




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Histoplasmosis

Pneumonia facts

  • Pneumonia is a lung infection that can be caused by different types of microorganisms, including bacteria, viruses, and fungi.
  • Symptoms of pneumonia include cough with sputum production, fever, and sharp chest pain on inspiration (breathing in).
  • Pneumonia is suspected when a doctor hears abnormal sounds in the chest, and the diagnosis is confirmed by a chest X-ray.
  • Bacteria causing pneumonia can be identified by sputum culture.
  • A pleural effusion is a fluid collection around the inflamed lung.
  • Bacterial and fungal (but not viral) pneumonia can be treated with antibiotics.

What is pneumonia?

Pneumonia is an infection of one or both lungs which is usually caused by bacteria, viruses, or fungi. Prior to the discovery of antibiotics, one-third of all people who developed pneumonia subsequently died fro...

Read the Pneumonia article »







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