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February 10, 2010
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High Blood Pressure Treatment (cont.)

Is alternative medicine used to treat high blood pressure?

Alternative medicine, also called integrative or complementary medicine, features the use of non-traditional (at least in the western world) techniques for treatment. For example, self-relaxation approaches to the therapy of hypertension include yoga, biofeedback, and meditation. These techniques can be effective in lowering the blood pressure, at least temporarily. In order to produce sustained reductions in the blood pressure these techniques may require hours of diligent adherence daily. They are generally practical only for few, highly motivated individuals with hypertension. Acupuncture has not yet been established as a standard or proven therapy for hypertension in the western world.

Certain herbal remedies have blood pressure-lowering components that may well be effective in treating hypertension. Most herbal remedies are available as food supplements, and the Food and Drug Administration (FDA) does not approve them as drugs. Therefore, herbal treatments for hypertension have not yet been adequately evaluated in scientifically controlled clinical trials for effectiveness and safety. In particular, their long-term side effects are unknown. A major problem with most herbal treatments is that their contents are not standardized. The ways in which herbal treatments work to lower blood pressure are not known and currently herbal remedies are usually not recommended for the treatment of hypertension.

What's new in high blood pressure?

A new class of anti-hypertensive drug, called a vasopeptidase blocker (inhibitor), has been developed. Uniquely, it works on two different systems at the same time. It blocks that part of the renin-angiotensin-aldosterone hormonal system that narrows (constricts) the peripheral arteries. It also blocks that part of the body's salt regulating system that conserves salt. Accordingly, this class of drug decreases the blood pressure by simultaneously dilating the peripheral arteries and increasing the body's loss of salt (natriuresis).

One such drug that is currently being studied is called omapatrilat. In laboratory animals with high blood pressure, this drug reduces the blood pressure and appears to protect the end-organs (heart, kidney, and brain) from damage by the high blood pressure. Moreover, the drug dilates the peripheral arteries, which increases blood flow to all tissues, and improves cardiac function in hypertensive patients with heart failure. Not yet approved by the FDA, omapatrilat is undergoing further testing to evaluate its effectiveness and safety.


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