Blood Pressure Medication

Pharmacy Author: Omudhome Ogbru, PharmD
Medical Editor: Jay W. Marks, MD

ACE inhibitors

ACE inhibitors are medications that slow the activity of the enzyme ACE, which decreases the production of angiotensin II (a very potent chemical that causes the muscles surrounding blood vessels to contract, thus narrowing the vessels). As a result, the blood vessels enlarge or dilate, and blood pressure is reduced.

Angiotensin II is a very potent chemical that is formed by the enzyme angiotensin converting enzyme (ACE). Angiotensin II is released within the body and causes the muscles surrounding blood vessels to contract, thus narrowing the vessels and increasing blood pressure. ACE inhibitors are medications that inhibit the activity of ACE which decreases the production of angiotensin II. As a result, ACE inhibitors cause the blood vessels to enlarge or dilate, and this reduces blood pressure.



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