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 Herpes Simplex Infections (Non-Genital) Main Article |  Glossary |  Herpes Simplex Infections (Non-Genital) Index 

Herpes Simplex Infections (Cold Sores, Non-Genital) Glossary of Terms

The following are health and medical definitions of terms that appear in the Herpes Simplex Infections (Cold Sores, Non-Genital) article.

Acetaminophen: A pain reliever and fever reducer. Brand name: Tylenol. The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold (that is, by requiring a greater amount of pain to develop before it is felt by a person). Acetaminophen reduces fever through its action on the heat-regulating center (the "thermostat") of the brain. Generic is available.

Acidophilus: Bacteria found in yogurt that can help restore a supportive bacterial environment to an intestinal tract whose normal intestinal bacterial population ("flora") has been disturbed by disease or antibiotics.
See the entire definition of Acidophilus

Acyclovir : (Brand name: Zovirax) One of a group of antiviral drugs that acts against the herpes viruses, including:

  • Herpes simplex 1 which causes cold sores
  • Herpes simplex 2 which causes genital herpes
  • Varicella-zoster which causes both chickenpox and shingles
  • Epstein-Barr virus which causes infectious mononucleosis
Acyclovir inhibits the replication of viral DNA needed to reproduce itself. Virally infected cells absorb more acyclovir than normal cells and convert more of it to an active form which prolongs its antiviral activity where it is most needed. Acyclovir may reduce the severity and duration of a shingles attack if given soon after the onset of symptoms.
See the entire definition of Acyclovir

Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
See the entire definition of Anemia

Antibody: An immunoglobulin, a specialized immune protein , produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production.
See the entire definition of Antibody

Antiviral: An agent that kills a virus or that suppresses its ability to replicate and, hence, inhibits its capability to multiply and reproduce.
See the entire definition of Antiviral

Arms: An appendage in anatomy and in clinical trials. See: Arm.

Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
See the entire definition of Aspirin

Blindness: Loss of useful sight. Blindness can be temporary or permanent. Damage to any portion of the eye, the optic nerve, or the area of the brain responsible for vision can lead to blindness. There are numerous (actually, innumerable) causes of blindness. The current politically correct terms for blindness include visually handicapped and visually challenged.
See the entire definition of Blindness

Blister: A collection of fluid underneath the top layer of skin (epidermis). One that is more than 5 mm in diameter with thin walls and is full of watery fluid is called a bulla or a bleb. There are many causes of blisters including burns , vesicant agents, friction forces, and diseases of the skin.
See the entire definition of Blister

Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.

Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
See the entire definition of Brain

Breastfeeding: Feeding a child human breast milk . According to the American Academy of Pediatrics , human breast milk is preferred for all infants. This includes even premature and sick babies, with rare exceptions. It is the food least likely to cause allergic reactions; it is inexpensive; it is readily available at any hour of the day or night; babies accept the taste readily; and the antibodies in breast milk can help a baby resist infections.
See the entire definition of Breastfeeding

Chemotherapy : 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915).
2. In oncology, drug therapy for cancer. Also called "chemo" for short.
See the entire definition of Chemotherapy

Childhood: (1) The time for a boy or girl from birth until he or she is an adult. (2) The more circumscribed period of time from infancy to the onset of puberty .
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
See the entire definition of Chronic

Cold sore: A small sore situated on the face or in the mouth that causes pain, burning, or itching before bursting and crusting over. The favorite locations are on the lips, chin or cheeks and in the nostrils. Less frequented sites are the gums or roof of the mouth (the palate).


See the entire definition of Cold sore

Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
See the entire definition of Complication

Condition: The term "condition" has a number of biomedical meanings including the following:

  1. An unhealthy state, such as in "this is a progressive condition."
  2. A state of fitness, such as "getting into condition."
  3. Something that is essential to the occurrence of something else; essentially a "precondition."
  4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.

Dehydration : Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
See the entire definition of Dehydration

Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
See the entire definition of Diarrhea

DNA: Deoxyribonucleic acid. One of two types of molecules that encode genetic information. (The other is RNA . In humans DNA is the genetic material; RNA is transcribed from it. In some other organisms, RNA is the genetic material and, in reverse fashion, the DNA is transcribed from it.)
See the entire definition of DNA

Encephalitis: Inflammation of the brain. Encephalitis occurs, for example, in 1 in 1,000 cases of measles . It may start (up to 3 weeks) after onset of the measles rash and present with high fever , convulsions, and coma. It usually runs a blessedly short course with full recovery within a week. Or it may eventuate in central nervous system impairment or death.
See the entire definition of Encephalitis

Erythema: A redness of the skin resulting from inflammation, for example, as caused by sunburn.

Erythema nodosum : An inflammatory reaction deep in the skin characterized by the presence of tender red lumps or nodules ranging in size from 1 to 5 centimeters most commonly located over the shins but occasionally involving the arms or other areas.
See the entire definition of Erythema nodosum

Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
See the entire definition of Fever

Flu: Short for influenza. The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia. Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.

Ganglion: The celebrated 2nd century Greek physician Galen ((c. 130-201 A.D.) who lived and worked in Rome first used the word ganglion to denote a nerve complex. Ganglion still is used to refer to an aggregation of nerve cell bodies. Another use of the word ganglion is for a tendon cyst that most commonly pops up near the wrist.
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Genetic: Having to do with genes and genetic information.

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)

Genital herpes: A viral infection transmitted through intimate contact with the moist mucous linings of the genitals. This contact can involve the mouth, the vagina or the genital skin. The herpes simplex type 2 (HSV-2) enters the mucous membranes through microscopic tears. Once inside the body, HSV-2 travels to nerve roots near the spinal cord and settles there permanently. When an infected person has a herpes outbreak, the virus travels down the nerve fibers to the site of the original infection and when it reaches the skin, the classic redness and blisters occur.
See the entire definition of Genital herpes

Gray: A unit of absorbed radiation equal to the dose of one joule of energy absorbed per kilogram of matter, or 100 rad . The unit is named for the British physician L. Harold Gray (1905-1965), an authority on the use of radiation in the treatment of cancer. The abbreviation for a gray is Gy. See also: Milligray .
See the entire definition of Gray

Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
See the entire definition of Headache

Herpes: A family of viruses. Herpes also refers to infection with one of the human herpesviruses, especially herpes simplex types 1 and 2.
See the entire definition of Herpes

Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever. Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.

Immune: Protected against infection. The Latin immunis means free, exempt.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunocompromised: Having an immune system that has been impaired by disease or treatment.
See the entire definition of Immunocompromised

Indication: 1. In medicine, a condition which makes a particular treatment or procedure advisable. CML (chronic myeloid leukemia) is an indication for the use of Gleevec (imatinib mesylate). 2. A sign or a circumstance which points to or shows the cause, pathology, treatment, or outcome of an attack of disease. The presence of the Philadelphia chromosome in peripheral blood cells is an indication of a relapse in CML.

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
See the entire definition of Inflammation

Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
See the entire definition of Itching

Labial: Pertaining to the lip, one of the fleshy folds which surround the opening of the mouth or the vagina.
See the entire definition of Labial back to top

Labial herpes: A small sore situated on the face or in the mouth that causes pain, burning, or itching before bursting and crusting over. The favorite locations are on the lips (the labia), chin or cheeks and in the nostrils. Less frequented sites are the gums or roof of the mouth (the palate).


See the entire definition of Labial herpes

Lactobacillus: A bacterium normally found in the mouth, intestinal tract, and vagina. Lactobacillus can also live in fermenting products, such as yogurt. Humans appear to have a symbiotic relationship with this bacteria. Lactobacillus has been with us so long that some types have become an important part of food digestion, although Lactobacillus can also contribute to cavities in the teeth if allowed to remain too long within the mouth.
See the entire definition of Lactobacillus

Lactobacillus acidophilus: The bacteria found in milk and fermented milk products, particularly yogurt with "live cultures" of L. acidophilus. L. acidophilus assists with the digestive process within the intestinal tract. It can be decimated by the use of antibiotics, and many health professionals urge people to use probiotics to counter this unfortunate side effect of antibiotic use.
See the entire definition of Lactobacillus acidophilus

Latent: Hidden, dormant, inactive.
See the entire definition of Latent

Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
See the entire definition of Lesion

Lip: One of the two fleshy folds which surround the opening of the mouth.
See the entire definition of Lip

Lips: Aside from the lips of the mouth, there are two pairs of lips at the entrance to the vagina. They are the labia majora (the larger outside pair) and the labia minora (the smaller inside pair). Together they form part of the vulva (the female external genitalia).

Lysine: An amino acid, one of the 20 building blocks of protein. A dietary essential amino acid, lysine is present in many proteins and is necessary for optimal growth in childhood. Symbol: Lys.

Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Mucosa: Having to do with a mucous membrane. For example, the oral mucosa.

Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
See the entire definition of Neck

Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.

Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.

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Ocular: Having to do with the eye.
See the entire definition of Ocular

Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
See the entire definition of Onset

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
See the entire definition of Pain

Palate: The roof of the mouth. The front portion is bony (hard palate), and the back portion is muscular (soft palate).
See the entire definition of Palate

Pharmacist: A professional who fills prescriptions, and in the case of a compounding pharmacist, makes them. Pharmacists are familiar with medication ingredients, interactions, cautions, and hints.
See the entire definition of Pharmacist

Pimples: Small papules or pustules. See: Pimple.

Pregnancy : The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
See the entire definition of Pregnancy

Pregnant: The state of carrying a developing fetus within the body.
See the entire definition of Pregnant

Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
See the entire definition of Primary

Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.

Rash : Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem.
See the entire definition of Rash

Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.

Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
See the entire definition of Recurrence

Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.

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Replication: A turning back, repetition, duplication, reproduction.
See the entire definition of Replication

Resolution: In genetics , resolution refers to the degree of molecular detail on a physical map of DNA , ranging from low to high.
See the entire definition of Resolution

Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
See the entire definition of Sensation

Sign: Any objective evidence of disease. Gross blood in the stool is a sign of disease. It can be recognized by the patient, doctor, nurse, or others. In contrast, a symptom is, by its nature, subjective. Abdominal pain is a symptom. It is something only the patient can know.
See the entire definition of Sign

Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.


See the entire definition of Skin

Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

See the entire definition of Sore

Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
See the entire definition of Stage

Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
See the entire definition of Stress

Sunburn: Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from tanning beds and booths that emit UV radiation . Sunburn is manifested by reddened, painful skin that may develop blisters.
See the entire definition of Sunburn

Sunscreen: A substance that blocks the effect of the sun's harmful rays. Using lotions that contain sunscreens can reduce the risk of skin cancer, including melanoma.

Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.

Symptomatic: 1 With symptoms, as a symptomatic infection. 2 Characteristic, as behavior symptomatic of Huntington disease. 3 Directed at the symptoms, as symptomatic treatment.

Therapy: The treatment of disease .
See the entire definition of Therapy

Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes.
See the entire definition of Tongue

Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.
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Trauma: Any injury , whether physically or emotionally inflicted. "Trauma" has both a medical and a psychiatric definition. Medically, "trauma" refers to a serious or critical bodily injury, wound, or shock . This definition is often associated with trauma medicine practiced in emergency rooms and represents a popular view of the term. In psychiatry , "trauma" has assumed a different meaning and refers to an experience that is emotionally painful, distressful, or shocking, which often results in lasting mental and physical effects.
See the entire definition of Trauma

Ulcer: An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue.
See the entire definition of Ulcer

Ultraviolet radiation: Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation can burn the skin and cause skin cancer .
See the entire definition of Ultraviolet radiation

Vaccines: Microbial preparations of killed or modified microorganisms that can stimulate an immune response in the body to prevent future infection with similar microorganisms. These preparations are usually delivered by injection.
See the entire definition of Vaccines

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash ."
See the entire definition of Viral

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
See the entire definition of Virus

Vitamins: The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines.
See the entire definition of Vitamins

Yeast: A group of single-celled fungi that reproduce by budding.
See the entire definition of Yeast

Zovirax: Brand name of Acyclovir.

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