Hepatitis C (cont.)
Medical Author:
Suresha Rajaguru, MD
Medical Author:
Mary D. Nettleman, MD, MS, MACP
Mary D. Nettleman, MD, MS, MACPMary D. Nettleman, MD, MS, MACP is the Chair of the Department of Medicine at Michigan State University. She is a graduate of Vanderbilt Medical School, and completed her residency in Internal Medicine and a fellowship in Infectious Diseases at Indiana University. Medical Editor:
Jay W. Marks, MD
Jay W. Marks, MDJay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles. In this Article
 What are the symptoms of hepatitis C infection?
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About 75% of people have no symptoms when they first acquire HCV infection. The remaining 25% may complain of fatigue, loss of appetite, muscle aches or fever. Yellowing of the skin or eyes (jaundice) is rare at this early stage of infection. Over time, people with chronic infection may begin to experience the effects of the persistent inflammation of the liver caused by the immune reaction to the virus. Blood tests may show elevated levels of liver enzymes, a sign of liver damage, which is often the first suggestion that the infection may be present. Patients may become easily fatigued or complain of nonspecific symptoms. As cirrhosis develops, symptoms increase and may include:
In patients with advanced cirrhosis, the liver begins to fail. This is a life-threatening problem. Confusion and even coma (encephalopathy) may result from the inability of the liver to process certain toxic substances. Increased pressure in the blood vessels of the liver (portal hypertension) may cause fluid to build up in the abdominal cavity (ascites) and result in engorged veins in the swallowing tube (esophageal varices) that tear easily and can bleed suddenly and massively. Portal hypertension also can cause kidney failure or an enlarged spleen resulting in a decrease of blood cells and the development of (anemia), or the development of low platelets (thrombocytopenia), which can promote bleeding. In advanced cirrhosis, liver failure causes decreased production of clotting factors. Patients with advanced cirrhosis often develop jaundice because the damaged liver is unable to eliminate a yellow compound, called bilirubin that is formed from the hemoglobin of old red blood cells. Reviewed by Jay W. Marks, MD on 1/2/2013 Patient CommentsViewers share their comments
Hepatitis C - Symptoms
Question: What symptoms did you experience with hepatitis C?
Hepatitis C - Treatment
Question: What was or has been the treatment for your hepatitis C, and was it effective?
Hepatitis C - Treatment Side Effects Experience
Question: Did you experience any side effects from your hepatitis C treatment, and if so, what were they?
Hepatitis C - Diagnosis
Question: What kinds of tests did you have to diagnose your hepatitis C?
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