Safe and effective use of hepatitis A/B vaccine in patients younger than 18 years of age has not been established.
DRUG INTERACTIONS: Hepatitis A/B vaccine vaccines should not be used with medications and therapies that suppress the immune system such as adalimumab (Humira), belimumab (Benlysta), cyclosporine (Gengraf, Neoral, Sandimmune), azathioprine (Imuran), irradiation, and high doses of steroids because suppressing the immune system reduces the effectiveness of hepatitis A/B vaccine.
PREGNANCY: There are no adequate studies done on hepatitis A/B vaccine to determine safe and effective use in pregnant women. Hepatitis A/B vaccine should be given to pregnant women only if clearly needed.
SIDE EFFECTS: Side effects of hepatitis A/B vaccine are injection site soreness and pain, headache, fatigue, redness, diarrhea, nausea, and fainting. The tip caps of pre-filled syringes may contain latex which can cause allergic reactions in latex-sensitive people. Serious allergic reactions, abnormal heart beats, and hair loss have also been reported.
REFERENCE:FDA Prescribing Information.
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