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hepatitis A and hepatitis B (recombinant) vaccine (Twinrix)

Pharmacy Author: Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor: Jerry R. Balentine, DO, FACEP

Jerry R. Balentine, DO, FACEP

Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.

What is hepatitis-b-hepatitis-a vaccine-injectable, and how does it work (mechanism of action)?

Hepatitis A/B vaccine is a man-made combination vaccine containing inactivated hepatitis A virus strain and non-infectious hepatitis B virus surface antigen. Inactive Hepatitis A virus combined with hepatitis B antigens stimulates the immune system to develop immunity against hepatitis A and B virus infections. The FDA approved hepatitis A/B vaccine in May 2001.

What brand names are available for hepatitis-b-hepatitis-a vaccine-injectable?

Twinrix

Is hepatitis-b-hepatitis-a vaccine-injectable available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for hepatitis-b-hepatitis-a vaccine-injectable?

Yes

What are the side effects of hepatitis-b-hepatitis-a vaccine-injectable?

Side effects of hepatitis A/B vaccine are injection site soreness and pain, headache, fatigue, redness, diarrhea, nausea, and fainting. The tip caps of pre-filled syringes may contain latex which can cause allergic reactions in latex-sensitive people. Serious allergic reactions, abnormal heart beats, and hair loss have also been reported.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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