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hepatitis-a/hepatitis-b vaccine - injection, Twinrix

GENERIC NAME: HEPATITIS-A/HEPATITIS-B VACCINE - INJECTION (hep-uh-TIE-tuss B/hep-uh-TIE-tuss A)

BRAND NAME(S): Twinrix

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This combination medication is used to help prevent infection from the hepatitis A and B viruses. Hepatitis A infection can be mild with no symptoms or a severe illness that can rarely cause liver failure and death. Hepatitis B infection can cause serious problems including liver failure, persistent hepatitis B infection, cirrhosis, and liver cancer. Preventing infection with these viruses can prevent these problems.Hepatitis A/B combination vaccine is made from whole, killed hepatitis A virus and a genetically engineered (man-made in the laboratory) piece of hepatitis B virus. It does not contain live virus, so you can not get hepatitis from the vaccine. This vaccine causes the body to make immune defensive substances (antibodies) against hepatitis A and B viruses that can protect you from infection with them. Hepatitis A/B vaccine does not protect you from other virus infections (e.g., HIV virus which causes AIDS, hepatitis C/E, HPV virus which causes genital warts and other problems).The vaccine is recommended for persons at an increased risk of getting these infections. Those at an increased risk include health care personnel, laboratory workers who handle blood and patient specimens, police, fire and emergency medical personnel who give first aid treatment, hemophiliacs, dialysis patients, household and intimate contacts of persons with persistent hepatitis B or active hepatitis A infections, persons with multiple sex partners, men who have sex with men, sex workers, injection drug abusers, and persons traveling to high-risk areas.

HOW TO USE: Read the Vaccine Information Statement available from your health care provider before receiving the vaccine. If you have any questions, consult your health care provider.This vaccine is usually given by injection into the shoulder muscle by a health care professional. Hepatitis A/B vaccine is a slightly milky, white suspension. Before giving this medication, inspect it visually for particles or discoloration. If either is present, do not use the liquid. Shake the vial or prefilled syringe well before giving the dose. Do not dilute. Use the full recommended dose of the vaccine. Discard any remaining vaccine left in single-dose vials.A series of 3 injections is usually given over 6 months. Your doctor will give you a vaccination schedule, which must be followed closely for best effectiveness. If you have an infection with fever at the time a vaccination is scheduled, your doctor may choose to delay the injection until you are better.Dosage is based on your age. Different brands of hepatitis A/B vaccine are available for different ages and may be given differently.If you are receiving the first hepatitis A/B vaccine injection at a time when your doctor feels you may have been exposed to either hepatitis A or B, you will also receive an injection of immune globulin. Immune globulin is a dose of antibodies against the viruses and will immediately help protect you from developing an infection. These antibodies only last a few months. For long-term protection, it is important to follow your vaccination schedule exactly.




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hepatitis-a/hepatitis-b vaccine - injection, Twinrix

What is hepatitis?

The term 'hepatitis' simply means inflammation of the liver. Hepatitis may be caused by a virus or a toxin such as alcohol. Other viruses that can cause injury to liver cells include the hepatitis A and hepatitis C viruses. These viruses are not related to each other or to hepatitis B virus and differ in their structure, the ways they are spread among individuals, the severity of symptoms they can cause, the way they are treated, and the outcome of the infection.

What is the scope of the problem?

Hepatitis B is an infection of the liver caused by the hepatitis B virus (HBV). It is estimated that 350 million individuals worldwide are infected with the virus, which causes 620,000 deaths worldwide each year. According to the Centers for Disease Control (CDC), approximately 46,000 new cases of hepatitis B occurred in the United States in 2006.

In the United States, rates of new infection were highest ...

Read the Hepatitis B article »




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