hepatitis A and hepatitis B (recombinant) vaccine (Twinrix)

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GENERIC NAME: Hepatitis A and Hepatitis B (Recombinant) vaccine


DRUG CLASS AND MECHANISM: Hepatitis A/B vaccine is a man-made combination vaccine containing inactivated hepatitis A virus strain and non-infectious hepatitis B virus surface antigen. Inactive Hepatitis A virus combined with hepatitis B antigens stimulates the immune system to develop immunity against hepatitis A and B virus infections. The FDA approved hepatitis A/B vaccine in May 2001.




  • Hepatitis A/B vaccine is available as sterile, preservative-free, intramuscular injections.
  • Hepatitis A/B vaccine injections are available in 1 ml single-dose vials and 1 ml single-dose pre-filled disposable syringes.
  • Each 1 ml dose of vaccine contains 720 ELISA Units of inactivated Hepatitis A virus and 20 mcg of recombinant Hepatitis B antigen protein.

STORAGE: Store hepatitis A/B vaccine under refrigeration between 2 C and 8 C (36 F and 46 F). Do not freeze hepatitis A/B vaccine vaccines and discard if they have been frozen.

PRESCRIBED FOR: Hepatitis A/B vaccine is used for active immunization against hepatitis A and all types of hepatitis B virus infections. Immunization is recommended for all susceptible adults who will be at risk for exposure to hepatitis A and hepatitis B virus. The CDC website can be consulted by travelers to determine regions that are at high risk for hepatitis A and B.

Medically Reviewed by a Doctor on 11/20/2014

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