DOSING: Doses vary considerably based on use and desired level of anticoagulation. Consult published guidelines for various uses (myocardial infarction, DVT, pulmonary embolism, for example) and the manufacturer's recommendations as dosage varies; some patients may require dosage adjustments if they have certain conditions (for example, renal or liver problems).
DRUG INTERACTIONS: Medications that increase the risk of bleeding will add to the effects of heparin and further increase the risk of bleeding that is associated with heparin. Such medications include aspirin, clopidogrel (Plavix), warfarin (Coumadin), other anticoagulants, and nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin; Advil), naproxen (Naprosyn), diclofenac (Voltaren), and others.
PREGNANCY: Heparin has not been adequately evaluated in pregnant women. Heparin should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Preservative-free heparin is recommended when heparin is needed during pregnancy.
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