• Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

GENERIC NAME: heparin sodium

BRAND NAME: Hemochron, Hep-Lock, Hep-Lock U/P, Heparin in 5% Dextrose, Heparin Lock Flush, HepFlush-10

DRUG CLASS AND MECHANISM: Heparin is a widely used injectable anticoagulant (stops the formation of blood clots). The blood coagulation system is composed of various steps and heparin acts at multiple sites in this process. Heparin prevents blood clots by blocking the action of two of the 12 clot-promoting proteins in blood (factors X and II) whose action is necessary for blood to clot. The FDA approved heparin in 1939.



PREPARATIONS: Injectable Solution: 1000, 2500, 5000, 10000, 20000 units/ml.

Heparin Lock Flush: 10, 100 units/ml.

Premixed Solution: 20000 units/500 ml, 25000 units/250 ml, 25000 units/500 ml.

STORAGE: Heparin sodium injections should be stored at 20 C to 25 C (68 F to 77 F).

PRESCRIBED FOR: Heparin sodium injection is used for various conditions, including prevention and treatment of venous thrombosis and pulmonary embolism, thromboembolic complications or blood clots associated with atrial fibrillation (a type of irregular heart beat), treatment of disseminated intravascular coagulation, and prevention of blood clots during heart and arterial surgery. It is also used in prevention and treatment of peripheral arterial embolism or clots, prevention of blood clots during blood transfusion, dialysis, and in extracorporeal circulation. Heparin is also used for treating acute coronary syndromes.

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