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February 10, 2012

Patient Discussions: Hemoglobin - Helped With Your Diagnosis

Question:Please describe how Hemoglobin has helped in your diagnosis.

Comment from: 25-34 Female (Patient) Published: July 19

My hemoglobin levels have always been very low with very high bilirubin levels. I was diagnosed with Gilbert's disease, which causes high bilirubin levels. My skin turns yellow when I am sick with a virus, and the whites of my eyes have always been yellow. After two miscarriages, my OBGYN sent me to a hemotologist just to see if there was anything going on. After going through several blood tests and a painful bone marrow aspiration, it was determined that I in fact have hereditary spherocytosis. It all began to click with all of my symptoms ... yellow skin and eyes, gallbladder removal at early age, enlarged spleen, anemia, hemoglobins always hang around 8 or 9 (especially during pregnancies -- hemoglobin at one point was a 5 but mostly stayed around 7 or 8). I then began to look at my dad who exhibits all of those same traits! Now my daughter has it (17 months old), and is treated by a pediatric hemotologist. Just thought this info might help someone seeking answers to their own symptoms!

Related Reading: hemoglobin | enlarged spleen | anemia

Comment from: JCB7057, 45-54 Male (Patient) Published: April 05

I just turned 50, and I was very tired and had no energy. I went into the doctor and they did the blood test and found that my hemoglobin was 7.0. After many tests, they found that my spleen was enlarged and spots near my colon. After a bone marrow test, they found I had non-Hodgkin's lymphoma -- cancer. I have since been through my chemo treatments and have been cancer-free. My hemoglobin is on the rise.

Related Reading: non-Hodgkin's lymphoma | cancer

Comment from: ashysmom, 3-6 Female (Caregiver) Published: October 25

I am the mother of a wonderful 5 year old girl. From the time she was only three days old we found out that she had hereditary spherocytosis. She had one blood transfusion when she was about a month old. Then, out of nowhere, this July we took her to the hospital because she was very tired and yellow. Her hemoglobin was at 4. The doctor said that she could have heart failure. The doctors have always told us that she is okay if she stays above 11. Well she is very yellow and tired again, so I took her to the doctor again today, which by the way, if you live in a small town like ours make sure your children only get sick Monday through Friday because the doctors, nurses and hospital staff get really inconvenienced when you show up on a Saturday, anyways, her levels are at 10.4, and they sent us home. They told us to "keep an eye on her." Luckily my sister in law is a nurse. She is a great help. Please! Just watch your children for these rare signs. This is a tricky little blood disorder!

Related Reading: blood transfusion | heart failure

Comment from: PrYnceZzMommA, 19-24 Female (Patient) Published: July 15

I am a 24 year old female, and I just delivered twins via c-section. At my 1 week postpartum appointment to have my staples taken out, they checked my hemoglobin because the nurse said that it had been low during my pregnancy. When they check it, it was a 7. The nurse said I looked very fatigued, said my skin was pretty pale. I was curious as to why I keep falling asleep all the time. It is so difficult to stay awake. I've always had a lower number, around a 10, but now it's lower. I am starting on iron pills to see if that will help, along with iron-rich foods. Hopefully, that helps. I need my energy back to take care of my 4 kids, all 4 and under.

Related Reading: c-section | pregnancy

Comment from: family manager, 45-54 Female (Patient) Published: May 21

It should be mentioned that an elevated hemoglobin can be indicative of hemochromatosis, which is iron overload. This is a genetic disorder that causes your body to hold on to iron and store it in the major organs. It can be fatal if not treated early. If one has an elevated hgb, other blood work (TIBC, saturation and serum ferritn) should be checked. There is no cure for hemochromatosis but if detected early one can live a long,healthy live by giving blood and adhering to a low iron diet. I personally had a high hgb with no other signs - iron level high normal, sat within normal limits - only when I pressed further genetic testing (because of family history) did I find out that I have hemochromatosis. Now I give blood and watch my diet and keep my levels on the low side of normal

Related Reading: hemochromatosis



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    • Kidney Failure
      • Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, medication. Some of the renal causes of kidney failure are from sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones. Treatment options included diet, medications, or dialysis.
    • Dehydration
      • Dehydration is the excessive loss of body water. There are a number of causes of dehydration including heat exposure, prolonged vigorous exercise, and some diseases of the gastrointestinal tract. The best way to treat dehydration is to prevent it from occurring.
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      • Anemia is the condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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      • Colon cancer is a malignancy that arises from the inner lining of the colon. Most, if not all, of these cancers develop from colonic polyps. Removal of these precancerous polyps can prevent colon cancer.
    • Stool Color & Texture Changes (Black, Red, Maroon, Green, Yellow, Gray, Tarry, Sticky)
      • Stool color is generally brown. When stool color changes, often, an individual becomes concerned. The presence of the bilirubin in bile is generally responsible for stool color. Bilirubin concentration can vary bile color from light yellow to almost black in color. Changes in bilirubin can cause stool to turn green, gray, or clay-like in color. Intestinal bleeding may turn stool black, tarry, red, maroon, or smelly stool. Medication and food may also affect stool color.
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      • COPD (chronic obstructive pulmonary disease) is a disorder that persistently obstructs bronchial airflow. COPD mainly involves three related conditions, chronic bronchitis, chronic asthma, and emphysema. Symptoms of COPD include chronic cough, shortness of breath, frequent respiratory infections, wheezing, morning headaches, and pulmonary hypertension. Treatment of COPD is focused on the related condition(s).
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      • Emphysema is a progressive disease of the lungs. The primary cause of emphysema is smoking. Alpha 1-antitrypsin deficiency is a rare disorder that has a genetic predisposition to emphysema. Aging, IV drug use, immune deficiencies, and connect tissue illnesses are also risk factors for emphysema. Emphysema is a subtype of COPD (chronic obstructive pulmonary disease, COLD). Symptoms include shortness of breath and wheezing. Management of symptoms may be achieved with medications, quitting smoking, pulmonary rehabilitation, or surgery.
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      • Pernicious anemia is a blood disorder in which the body does not make enough red blood cells due to a lack of vitamin B12 in the blood. Pernicious anemia can develop from a lack of a protein that helps the body absorb vitamin B12, not getting enough B12 in the diet, and certain intestinal conditions that interfere with the absorption of vitamin B12 such as Crohn's disease, celiac sprue, or ulcerative colitis. There is no cure for pernicious anemia, thus treatment is life-long.
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      • Sickle cell anemia (sickle cell disease), a blood disease which shortens life expectancy, is cause by an inherited abnormal hemoglobin. Symptoms may include bacterial infections, painful swelling of the hands and feet, fever, leg ulcers, fatigue, anemia, eye damage, and lung and heart injury. Treatment for sickle cell anemia aims to manage and prevent the worst manifestations of the disease and focuses on therapies that block red blood cells from stacking together, which can lead to tissue and organ damage and pain.
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      • G6PD deficiency (Glucose 6-phosphate dehydrogenase) leads to a condition called hemolytic anemia. Causes of G6PD deficiency is an abnormal gene located in the X-chromosome, therefore, it is more common in males. Hemolytic anemia caused by G6PD deficiency generally occurs after exposure to malaria medications, antiitching drugs, and fava beans. Pneumonia and other infections can also precipitate hemolytic anemia in individuals with G6PD deficiency. Treatment is generally discontinuing the drug or compound treating infection. Blood transfusions are necessary in some individuals.
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Hemoglobin

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