Abdomen: The belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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ACE inhibitors : A drug that inhibits ACE (angiotensin converting enzyme) which is important to the formation of angiotensin II. Angiotensin II causes arteries in the body to constrict and thereby raises the blood pressure. ACE inhibitors lower the blood pressure by inhibiting the formation of angiotensin II. This relaxes the arteries. Relaxing the arteries not only lowers blood pressure, but also improves the pumping efficiency of a failing heart and improves cardiac output in patients with heart failure. ACE inhibitors are therefore used for blood pressure control and congestive heart failure .
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Adrenaline: A substance produced by the medulla (inside) of the adrenal gland, adrenaline (the official name in the British Pharmacopoeia) is synonymous with epinephrine. Technically speaking, adrenaline is a sympathomimetic catecholamine. It causes quickening of the heart beat, strengthens the force of the heart's contraction, opens up the bronchioles in the lungs and has numerous other effects. The secretion of adrenaline by the adrenal is part of the "fight-or-flight" reaction that we have in response to being frightened.
Aggressive: In oncology, quickly growing, tending to spread rapidly. As, for example, an aggressive tumor.
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Alzheimer's disease: See: Alzheimer disease.
Angina: Chest pain due to an inadequate supply of oxygen to the heart muscle. The chest pain of angina is typically severe and crushing. There is a feeling just behind the breastbone (the sternum) of pressure and suffocation.
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Angina pectoris: Chest pain that is typically severe and crushing with a feeling just behind the breastbone (the sternum) of pressure and suffocation, due to an inadequate supply of oxygen to the heart muscle. The term "angina pectoris" comes from the Latin "angere" meaning "to choke or throttle" + "pectus" meaning "chest". Angina pectoris was first described by the English physician William Heberden (1710-1801) and may be referred to simply as angina.
Angiography: A procedure performed to view blood vessels after injecting them with a radioopaque dye that outlines them on x-ray. This technique can be usefully used to look at arteries in many areas of the body, including the brain, neck (carotids), heart, aorta, chest, pulmonary circuit, kidneys, gastrointestinal tract, and limbs.
Angioplasty: Procedure with a balloon-tipped catheter to enlarge a narrowing in a coronary artery. Also called Percutaneous Transluminal Coronary Angioplasty (PTCA).
Angiotensin: A family of peptides (smaller than proteins) that act as vasoconstrictors to narrow blood vessels.
Angiotensin converting enzyme: Usually abbreviated ACE.
Anticoagulant: Any agent used to prevent the formation of blood clots.
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Arm: 1. In popular usage, the appendage that extends from the shoulder to the hand. However, the medical definition refers to the upper extremity extending from the shoulder only to the elbow, excluding the forearm, which extends from the elbow to the wrist. The arm contains one bone: the humerus. 2. In a randomized clinical trial, any of the treatment groups. Most randomized trials have two "arms," but some have three "arms," or even more.
Arms: An appendage in anatomy and in clinical trials. See: Arm.
Artery: A vessel that carries blood high in oxygen content away from the heart to the farthest reaches of the body. Since blood in arteries is usually full of oxygen, the hemoglobin in the red blood cells is oxygenated. The resultant form of hemoglobin (oxyhemoglobin) is what makes arterial blood look bright red.
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Atherosclerosis: A process of progressive thickening and hardening of the walls of medium-sized and large arteries as a result of fat deposits on their inner lining.
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Atherosclerotic: Pertaining to atherosclerosis, the process of progressive thickening and hardening of the walls of arteries from fat deposits on their inner lining. Atherosclerotic heart disease is the leading cause of death in the US.
Attention: The ability to focus selectively on a selected stimulus, sustaining that focus and shifting it at will. The ability to concentrate.
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Atypical: Not typical, not usual, not normal, abnormal. Atypical is often used to refer to the appearance of precancerous or cancerous cells.
Back pain: Pain felt in the low or upper back. There are many causes of back pain.
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Biochemical: Relating to biochemistry, the application of the tools and concepts of chemistry to living systems.
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Birth control : Birth control is the use of any practices, methods, or devices to prevent pregnancy from occurring in a sexually active woman. Also referred to as family planning, pregnancy prevention, fertility control, or contraception; birth control methods are designed either to prevent fertilization of an egg or implantation of a fertilized egg in the uterus.
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Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
Blood clot: Blood that has been converted from a liquid to a solid state. Also called a thrombus .
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Blood sugar: Blood glucose. See also: High blood sugar; Low blood sugar.
Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
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Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Breast : The breast refers to the front of the chest or, more specifically, to the mammary gland. The mammary gland is a milk producing gland. It is composed largely of fat. Within the mammary gland is a complex network of branching ducts. These ducts exit from sac-like structures called lobules, which can produce milk in females. The ducts exit the breast at the nipple.
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Breast cancer: Breast cancer is diagnosed with self- and physician-examination of the breasts, mammography, ultrasound testing, and biopsy. There are many types of breast cancer that differ in their capability of spreading to other body tissues (metastasis). Treatment of breast cancer depends on the type and location of the breast cancer, as well as the age and health of the patient. The American Cancer Society recommends that a woman should have a baseline mammogram between the ages of 35 and 40 years. Between 40 and 50 years of age mammograms are recommended every other year. After age 50 years, yearly mammograms are recommended.
Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
Bypass: An operation in which a surgeon creates a new tubular pathway for the movement of fluids and/or other substances in the body.
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CABG: Coronary artery bypass graft; and Coronary artery bypass grafting.
CAD: coronary artery disease. CAD is a major cause of illness and death. It begins when hard cholesterol substances (plaques) are deposited within a coronary artery. These arteries arise from the aorta adjacent to the heart and supply the heart muscle with blood that is rich in oxygen. They are called the coronary arteries because they encircle the heart in the manner of a crown.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cardiac: Having to do with the heart.
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Cardiopulmonary: Having to do with both the heart and lungs.
Cardiopulmonary resuscitation: The emergency substitution of heart and lung action to restore life to someone who appears dead. The two main components of cardiopulmonary resuscitation (CPR) are chest compression to make the heart pump and mouth-to-mouth ventilation to breath for the victim.
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Cardioversion: The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one. This conversion can be accomplished by pharmacologic means using medications or by electrical cardioversion using a defibrillator.
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Catheter: A thin, flexible tube . For example, a catheter placed in a vein provides a pathway for giving drugs, nutrients, fluids, or blood products. Samples of blood can also be withdrawn through the catheter.
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Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
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Chest pain: There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism. Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.
Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool , move through it to the rectum and leave the body through the anus . .
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Colon cancer: A malignancy that arises from the inner lining of the colon . Most, if not all, of these cancers develop from colonic polyps . Removal of these precancerous polyps can prevent colon cancer.
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Compression: 1. The act of pressing together. As in a compression fracture, nerve compression, or spinal cord compression.
2. To shorten in time. In embryology, there may be compression of development with some stages even omitted.
Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Contraction: The tightening and shortening of a muscle.
Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.
Coronary angiography: The most accurate method (the "gold standard") for evaluating and defining coronary artery disease (CAD). Coronary angiography is used to identify the exact location and severity of CAD.
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Coronary arteries: The vessels that supply the heart muscle with blood rich in oxygen. They are called the coronary arteries because they encircle the heart in the manner of a crown. The word "coronary" comes from the Latin "corona" and Greek "koron" meaning crown. Like other arteries, the coronaries may be subject to arteriosclerosis (hardening of the arteries). There are a number of coronary arteries. Those most often bypassed today include the right coronary artery, the posterior descending coronary artery, the left main coronary artery, the left anterior descending coronary artery and the left circumflex coronary artery. Plaques obstructing the coronary arteries may also be treated by balloon angioplasty , stents, and other techniques.
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Coronary artery bypass graft: Abbreviated CABG. A form of bypass surgery that can create new routes around narrowed and blocked coronary arteries, permitting increased blood flow to deliver oxygen and nutrients to the heart muscle. Coronary artery bypass graft is an option for selected groups of patients with significant narrowings and blockages of the heart arteries. The bypass graft for a CABG can be a vein from the leg or an inner chest-wall artery. CABG surgery is one of the most commonly performed major operations. Coronary artery disease develops because of hardening of the arteries (atherosclerosis) that supply blood to the heart muscle. Diagnostic tests prior to (and after) CABG include the electrocardiogram (EKG), stress test, echocardiogram, and coronary angiography.
Coronary artery disease: A major cause of illness and death, coronary artery disease (CAD) begins when hard cholesterol substances (plaques) are deposited within a coronary artery.
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CPR: Cardiopulmonary resuscitation. Also cardiac and pulmonary rehabilitation and computer-based patient records.
Creatine: A compound the body synthesizes (makes) and then utilizes to store energy. The storage of energy occurs when phosphate molecules are attached to creatine to create creatine phosphate. Creatine phosphate is capable of donating phosphate to ADP in order to make ATP . ATP can then be converted into ADP with release of energy.
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Dementia : Significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning.
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Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diabetes mellitus: Better known just as " diabetes " -- a chronic disease associated with abnormally high levels of the sugar glucose in the blood. Diabetes is due to one of two mechanisms:
(1) Inadequate production of insulin (which is made by the pancreas and lowers blood glucose) or
(2) Inadequate sensitivity of cells to the action of insulin.
The two main types of diabetes correspond to these two mechanisms and are called insulin dependent (type 1) and non-insulin dependent (type 2) diabetes. In type 1 diabetes there is no insulin or not enough of it. In type 2 diabetes, there is generally enough insulin but the cells upon it should act are not normally sensitive to its action.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diastolic: Referring to the time when the heart is in a period of relaxation and dilatation (expansion).
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Dysfunction: Difficult function or abnormal function.
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ECG: Abbreviation for electrocardiogram or EKG. The K is from "kardio" (in German).
Electrocardiogram : A recording of the electrical activity of the heart. An electrocardiogram is a simple, non-invasive procedure. Electrodes are placed on the skin of the chest and connected in a specific order to a machine that, when turned on, measures electrical activity all overaround the heart. Output is usually in the form of a long scroll of paper displaying a printed graph of activity. Newer models output the data directly to a computer and screen, although a print-out may still be made.
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Emboli: Something that travels through the bloodstream, lodges in a blood vessel and blocks it. Examples of emboli are a detached blood clot, a clump of bacteria , and foreign material such as air.
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Embolism: The obstruction of a blood vessel by a foreign substance or a blood clot blocking the vessel. Something travels through the bloodstream, lodges in a vessel and plugs it.
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Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions , converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction .
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Erectile dysfunction: A common men's health problem characterized by the consistent inability to sustain an erection sufficient for sexual intercourse or the inability to achieve ejaculation , or both. Impotence can vary. It can involve a total inability to achieve an erection or ejaculation, an inconsistent ability to do so, or a tendency to sustain only very brief erections. Erectile dysfunction is also called impotence ,
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Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.
Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Estrogens: Female hormones produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Fat: 1 Along with proteins and carbohydrates, one of the three nutrients used as energy sources by the body. The energy produced by fats is 9 calories per gram. Proteins and carbohydrates each provide 4 calories per gram. 2 Total fat; the sum of saturated, monounsaturated and polyunsaturated fats. Intake of monounsaturated and polyunsaturated fats can help reduce blood cholesterol when substituted for saturated fats in the diet. 3 A slang term for obese or adipose. 4 In chemistry, a compound formed from chemicals called fatty acids. These fats are greasy, solid materials found in animal tissues and in some plants. Fats are the major component of the flabby material of a body, commonly known as blubber.
Father: (1) The male parent. (2) One who originates. For example, "Wilhelm Roentgen is considered the father of radiology." (3) To produce offspring as a male. (4) To provide paternal protection and guidance to children.
Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Fats: Plural of the word "fat". See the definition of fat.
Fatty acids: Molecules that are long chains of lipid-carboxylic acid found in fats and oils and in cell membranes as a component of phospholipids and glycolipids. (Carboxylic acid is an organic acid containing the functional group -COOH.)
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Fibrillation: In matters of the heart (cardiology), fibrillation is incoordinate twitching of the heart muscle fibers.
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Folic acid: One of the B vitamins that is a key factor in the synthesis (the making) of nucleic acid (DNA and RNA).
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Gallbladder: A pear-shaped organ just below the liver that stores the bile secreted by the liver. During a fatty meal, the gallbladder contracts, delivering the bile through the bile ducts into the intestines to help with digestion. Abnormal composition of bile leads to formation of gallstones, a process termed cholelithiasis. The gallstones cause cholecystitis, inflammation of the gallbladder.
Genetic: Having to do with genes and genetic information.
Graft: Healthy skin, bone, or other tissue taken from one part of the body to replace diseased or injured tissue removed from another part of the body.
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Groin: In anatomy, the area where the upper thigh meets the trunk. More precisely, the fold or depression marking the juncture of the lower abdomen and the inner part of the thigh.
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HDL: High density lipoprotein.
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HDL cholesterol: Lipoproteins, which are combinations of lipids (fats) and proteins, are the form in which lipids are transported in the blood. The high-density lipoproteins transport cholesterol from the tissues of the body to the liver so it can be gotten rid of (in the bile). HDL cholesterol is therefore considered the "good" cholesterol. The higher the HDL cholesterol level, the lower the risk of coronary artery disease.
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart attack: The death of heart muscle due to the loss of blood supply. The loss of blood supply is usually caused by a complete blockage of a coronary artery, one of the arteries that supplies blood to the heart muscle. Death of the heart muscle, in turn, causes chest pain and electrical instability of the heart muscle tissue.
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Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease. Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.
Heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
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Heart muscle: A type of muscle with unique features only found in the heart. The heart muscle, or cardiac muscle, is medically called the myocardium ("myo-" being the prefix denoting muscle).
Heartburn: An uncomfortable feeling of burning and warmth occurring in waves rising up behind the breastbone (sternum) toward the neck. It is usually due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart. It is a popular nonmedical term. It is medically called pyrosis.
High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hirudin: An anticoagulant ("bloodthinner"). Hirudin is the active principle in the salivary secretion of leeches. The name hirudin is from Hirudo medicinalis, the name of the medicinal leech .
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Hormone therapy: A form of treatment that takes advantage of the fact that certain cancers depend on hormones to grow. Hormone therapy may include giving hormones to the patient or decreasing the level of hormones in the body.
Hot flashes: A sudden wave of mild or intense body heat caused by rushes of hormonal changes resulting from decreased levels of estrogen . Hot flashes can occur at any time and may last from a few seconds to a half-hour. They are due to blood vessel opening and constricting and a symptom of menopause .
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Hyperlipidemia: High lipid (fat) levels in the blood.
Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hysterectomy: A surgical operation to remove the uterus and, sometimes, the cervix . Removal of the entire uterus and the cervix is referred to as a total hysterectomy . Removal of the body of the uterus without removing the cervix is referred to as a subtotal hysterectomy .
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Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.
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Infarction: The formation of an infarct, an area of tissue death due to a local lack of oxygen.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.
Insertion: Chromosome abnormality due to insertion of a segment from one chromosome into another chromosome.
Insulin: A natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin.
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Interventional: Pertaining to the act of intervening, interfering or interceding with the intent of modifying the outcome. As, for example, an interventional radiologist.
Jaw: The bones below the mouth (the mandible) and the bone above the mouth just above the mouth (the maxilla). The word jaw comes from the Anglo-Saxon ceowan meaning to chew.
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LDL cholesterol: Lipoproteins which are combinations of lipids (fats) and proteins are the form in which lipids are transported in the blood. The low-density lipoproteins transport cholesterol from the liver to the tissues of the body. LDL cholesterol is therefore considered the "bad" cholesterol.
Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Lipid: Another word for "fat." (Please see the various meanings of Fat .) A lipid is more formally defined as a substance such as a fat, oil or wax that dissolves in alcohol but not in water. Lipids contain carbon, hydrogen and oxygen but have far less oxygen proportionally than carbohydrates .
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Lipoproteins: Complexes of lipid and protein, the way lipids travel in the blood.
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Lumen: A luminous term referring to the channel within a tube such as a blood vessel or to the cavity within a hollow organ such as the intestine . Lumen is a luminous term because it is Latin for light, including the light that comes through a window. When a hollow organ is cut across, you can see light through the space that has been opened. So the word "lumen" came to mean this space.
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Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
Malaise: A vague feeling of discomfort, one that cannot be pinned down but is often sensed as "just not right."
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Menopause : The time in a woman's life when menstrual periods permanently stop; it is also called the "change of life." Menopause is the opposite of the menarche.
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Molecule: The smallest unit of a substance that can exist alone and retain the character of that substance.
Mortality: A fatal outcome or, in one word, death. The word "mortality" is derived from "mortal" which came from the Latin "mors" (death). The opposite of mortality is, of course, immortality. Mortality is also quite distinct from morbidity (illness).
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Mortality rate: A death rate . There are a number of different types of mortality rates as, for examples, the following: - The fetal mortality rate : The ratio of fetal deaths to the sum of the births (the live births + the fetal deaths) in that year.
- The infant mortality rate : The number of children dying under a year of age divided by the number of live births that year.
- The maternal mortality rate : The number of maternal deaths related to childbearing divided by the number of live births (or by the number of live births + fetal deaths) in that year.
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Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Myocardial infarction: A heart attack . Abbreviated MI.
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National Cholesterol Education Program: NCEP. A program designed to reduce illness and death from coronary heart disease (CHD) in the US by reducing the percentage of Americans with high blood cholesterol. Through educational efforts directed at health professionals and the public, the NCEP aims to raise awareness and understanding about high blood cholesterol as a risk factor for CHD and the benefits of lowering cholesterol levels as a means of preventing CHD. NCEP was begun by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) in November 1985.
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Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.
NCEP: The National Cholesterol Education Program. See: National Cholesterol Education Program
Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
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Nicotine: An alkaloid (a nitrogen-containing chemical) made by the tobacco plant or produced synthetically. In the plant kingdom, nicotine is not restricted to tobacco but is widespread. The tobacco plant, Nicotiana tabacum, belongs to the nightshade family, which also includes potatoes, tomatoes, eggplant and red peppers. All contain nicotine. However, the concentration of nicotine in those vegetables is far lower than the level in tobacco. Nicotine has powerful pharmacologic effects (including increased heart rate, heart stroke volume, and oxygen consumption by the heart muscle) as well as powerful psychodynamic effects (such as euphoria, increased alertness, and a sense of relaxation). As is now well known, nicotine is also powerfully addictive. When someone becomes habituated to nicotine and then stops using it, they experience the symptoms of withdrawal, including anxiety, irritability, restlessness, shortened attention span and an intense, sometimes irresistible, craving for nicotine.
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Oophorectomy: The removal of one or both ovaries by surgery. Also known as ovariectomy.
Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pain unit: A measurement of the intensity of pain. See also: Dol.
Percutaneous: Through the skin, as in a percutaneous biopsy.
Percutaneous transluminal coronary angioplasty : PTCA. The use of a balloon-tipped catheter to enlarge a narrowed artery.
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Placebo: A "sugar pill" or any dummy medication or treatment.
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Plaque: 1. An semi-hardened accumulation of substances from fluids that bathe an area. Examples include dental plaque and cholesterol plaque.
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Platelet: An irregular, disc-shaped element in the blood that assists in blood clotting. During normal blood clotting, the platelets clump together (aggregate). Although platelets are often classed as blood cells, they are actually fragments of large bone marrow cells called megakaryocytes.
Postmenopausal: After the menopause . Postmenopausal is defined formally as the time after which a woman has experienced twelve (12) consecutive months of amenorrhea (lack of menstruation) without a period.
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Prevalence: The proportion of individuals in a population having a disease. Prevalence is a statistical concept referring to the number of cases of a disease that are present in a particular population at a given time.
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Probability: The likelihood that something will happen. For example, a probability of less than .05 indicates that the probability of something occurring by chance alone is less than 5 in 100, or 5 percent. This level of probability is usually taken as the level of biologic significance, so a higher incidence may be considered meaningful. The abbreviation for probability is P.
Progesterone: A female hormone and the principal progestational hormone that is made mainly by the corpus luteum in the ovary and by the placenta. Progesterone prepares the lining (endometrium) of the uterus (the womb) to receive and sustain the fertilized egg and so permits pregnancy. Similarly refers to synthetic versions of the hormone. Also known as progestational hormone.
Progestin: Any one of a group of steroid hormones that have the effect of progesterone.
Prognosis: 1. The expected course of a disease .
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good.
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Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
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Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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PTCA: Percutaneous transluminal coronary angioplasty. A procedure with a balloon-tipped catheter to enlarge a narrowing in a coronary artery. Often just called angioplasty.
Pulmonary: Having to do with the lungs. (The word comes from the Latin pulmo for lung).
Pulmonary embolism: The obstruction of the pulmonary artery or a branch of it leading to the lungs by a blood clot, usually from the leg, or foreign material causing sudden closure of the vessel. (Embolus is from the Greek "embolos" meaning plug.)
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Random: The process by which an outcome is determined solely by chance, for example, by a coin flip.
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Randomized: The use of chance alone to assign the participants in an experiment or trial to different groups in order to fairly compare the outcomes with different treatments. Randomization is an important feature of experimental design.
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Randomized controlled trial: (RCT) A study in which people are allocated at random (by chance alone) to receive one of several clinical interventions. One of these interventions is the standard of comparison or control. The control may be a standard practice, a placebo ("sugar pill"), or no intervention at all. Someone who takes part in a randomized controlled trial (RCT) is called a participant or subject. RCTs seek to measure and compare the outcomes after the participants receive the interventions. Because the outcomes are measured, RCTs are quantitative studies.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
Reperfusion: The restoration of blood flow to an organ or tissue. After a heart attack, an immediate goal is to quickly open blocked arteries and reperfuse the heart muscles. Early reperfusion minimizes the extent of heart muscle damage and preserves the pumping function of the heart.
Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.
Resuscitation: The procedure of restoring to life, as in cardiopulmonary resuscitation (CPR).
Risk factor: Something that increases a person's chances of developing a disease.
Rupture: A break or tear in any organ (such as the spleen) or soft tissue (such as the achilles tendon). Rupture of the appendix is more likely among uninsured and minority children when they develop appendicitis.
Saturated fat: A fat that is solid at room temperature and comes chiefly from animal food products. Some examples are butter, lard, meat fat, solid shortening, palm oil, and coconut oil. These fats tend to raise the level of cholesterol in the blood.
Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Shoulder: A structure made up of two main bones: the scapula (shoulder blade) and the humerus (the long bone of the upper arm). The end of the scapula, called the glenoid, is a socket into which the head of the humerus fits, forming a flexible ball-and-socket joint. The scapula is an unusually shaped bone. It extends up and around the shoulder joint at the rear to create a roof called the acromion and around the shoulder joint at the front to constitute the coracoid process. The shoulder joint is cushioned by cartilage that covers the face of the glenoid socket and the head of the humerus. The joint is stabilized by a ring of fibrous cartilage around the glenoid socket that is called the labrum. Ligaments connect the bones of the shoulder and tendons join these bones to surrounding muscles. The biceps tendon attaches the biceps muscle to the shoulder and helps stabilize the joint. Four short muscles that originate on the scapula pass around the shoulder where their tendons fuse together to form the rotator cuff.
Shoulder pain: Pain in the shoulder due to an injury or disease. The design of the shoulder joint is such that it sacrifices stability for mobility. As an extremely mobile joint that plays a central role in the action of a major extremity (the arm), the shoulder is at high risk for injury. An injury can involve the ligaments, bursae, or tendons surrounding the shoulder joint, the cartilage, menisci (plural for meniscus), or bones of the joint. Pain can also occur in the shoulder from diseases and conditions that involve the shoulder joint, the soft tissues and bones surrounding the shoulder, or the nerves that supply sensation to the shoulder area.
Sign: Any objective evidence of disease. Gross blood in the stool is a sign of disease. It can be recognized by the patient, doctor, nurse, or others. In contrast, a symptom is, by its nature, subjective. Abdominal pain is a symptom. It is something only the patient can know.
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Spasm: A brief, automatic jerking movement. A muscle spasm can be quite painful, with the muscle clenching tightly. A spasm of the coronary artery can cause angina. Spasms in various types of tissue may be caused by stress, medication, over-exercise, or other factors.
Statins: A class of drugs that lower cholesterol .
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Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Stroke : The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
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Substance: 1. Material with particular features, as a pressor substance.
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse.
Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Sweat: A colorless transparent acidic fluid with a distinctive odor secreted by the small tubular sudoriferous (sweat) glands situated within the skin and under it in the subcutaneous tissue . The sweat glands discharge their fluid through tiny openings in the surface of the skin.
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Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Systolic: The blood pressure when the heart is contracting. It is specifically the maximum arterial pressure during contraction of the left ventricle of the heart. The time at which ventricular contraction occurs is called systole.
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Therapy: The treatment of disease .
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Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus, - The bone marrow is a tissue;
- Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
- Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.
Tobacco: A South American herb, formally known as Nicotiana tabacum , whose leaves contain 2-8% nicotine and serve as the source of smoking and smokeless tobacco .
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Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes.
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Toothache: Pain in or near a tooth. Also called odontalgia. The most common cause of a toothache is a dental cavity. The second most common cause is gum disease. Toothache can be caused by a problem that does not originate from a tooth or the jaw.
tPA: See: Tissue plasminogen activator.
Variant angina : Chest pain due to coronary artery spasm, a sudden constriction of a coronary artery (one of the vessels that supply the heart muscle with blood rich in oxygen) depriving the heart muscle (myocardium) of blood and oxygen. This is also called Prinzmetal angina .
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Vascular: Relating to the blood vessels of the body. The blood vessels of the body, as a group, are referred to as the vascular system.
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Ventricular: Pertaining to the ventricles, the lower chambers of the heart, as in ventricular fibrillation and ventricular septal defect.
Ventricular fibrillation: An abnormal irregular heart rhythm whereby there are very rapid uncoordinated fluttering contractions of the lower chambers (ventricles) of the heart. Ventricular fibrillation disrupts the synchrony between the heartbeat and the pulse beat. Ventricular fibrillation is most commonly associated with heart attacks or scarring of the heart muscle from previous heart attack. It is life threatening. Ventricular fibrillation is most commonly associated with heart attacks or scarring of the heart muscle from previous heart attack. It is life threatening.
Vessel: A tube in the body that carries fluids: blood vessels or lymph vessels.
Women's Health Initiative: A long-term national health study that focuses on strategies for preventing heart disease, breast and colorectal cancer and osteoporosis in postmenopausal women. This 15-year project sponsored by the National Institutes of Health (NIH) involves over 161,000 women aged 50-79. The WHI Clinical Trial and Observational Study has three study components.See the entire definition of Women's Health Initiative
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From the Doctors at MedicineNet.com  |
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- Aspirin and Antiplatelet Medications - Read about aspirin therapy to prevent heart attack and stroke. Also learn about other anti-platelet medications such as, thienopyridines, and glycoprotein IIB/IIa inhibitors. Source:MedicineNet
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