haloperidol, Haldol (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

WARNING: Haloperidol may cause a condition called "orthostatic hypotension" during the early phase of treatment (first week or two). Orthostatic hypotension causes patients to become dizzy upon arising from a lying or sitting position because of a drop in blood pressure.

Haloperidol also may cause abnormal heart beats, sudden death, seizures, decreases in red and white blood cells, and withdrawal symptoms.

Elderly patients with dementia-related psychosis and treated with antipsychotic drugs such as haloperidol are at an increased risk of death.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS:

  • Tablets: 0.5, 1, 2, 5, 10, and 20 mg.
  • Oral Concentrate: 1 and 2 mg/ml. Injectable solution (lactate): 5 mg/ml;
  • Injectable solution (decanoate): 50 and 100 mg/ml.

STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F).

DOSING:

  • The recommended oral dose for schizophrenia is 0.5-5 mg two or three times daily up to a maximum dose of 30 mg daily. The lactate solution dose is 2-5 mg every 4-8 hours as needed by intramuscular injection. The lactate solution may also be administered by intravenous injection at 1-2 mg every 2-4 hours and titrated to effect. The maximum single injection dose is 50 mg and the maximum daily dose is 500 mg daily. The dose for the decanoate solution is 10-20 times the daily oral dose once monthly by intramuscular injection. The decanoate solution should not be administered intravenously.
  • The recommended dose for treating Tourette's syndrome is 0.5-5 mg orally two or three times daily.

DRUG INTERACTIONS: Haloperidol causes sedation, and sedation may be greater if haloperidol is taken with alcohol and other drugs than can cause sedation such as the benzodiazepine class of anti-anxiety drugs for example:

Medically Reviewed by a Doctor on 12/10/2014


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