Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: haloperidol
BRAND NAME: Haldol
DRUG CLASS AND MECHANISM: Haloperidol is an antipsychotic medication. It also is used to control tics and vocal utterances that are part of Tourette's syndrome. Haloperidol interferes with the effects of neurotransmitters in the brain which are the chemical messengers that nerves manufacture and release to communicate with one another. Haloperidol blocks receptors for the neurotransmitters (specifically the dopamine and serotonin type 2 receptors) on the nerves. As a result, the nerves are not "activated" by the neurotransmitters released by other nerves. Haloperidol was approved by the FDA in 1967.
GENERIC AVAILABLE: Yes
STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F).
PRESCRIBED FOR: Haloperidol is used for treating schizophrenia, acute psychosis, and for tics and vocal utterances of Tourette's syndrome.
DRUG INTERACTIONS: Haloperidol causes sedation, and sedation may be greater if haloperidol is taken with alcohol and other drugs than can cause sedation such as the benzodiazepine class of anti-anxiety drugs for example:
The narcotic class of pain medications and its derivatives for example:
The tricyclic class of antidepressants for example:
Some antihistamines for example:
Certain antihypertensive medications for example:
Carbamazepine (Tegretol) may increase the elimination of haloperidol, rendering the haloperidol less effective. Rifampin (Rifadin) may decrease the elimination of haloperidol, increasing the risk of side effects from haloperidol.
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