DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: anticholinergic medications (e.g., antispasmodics such as belladonna alkaloids, scopolamine), cabergoline, carbamazepine, ketoconazole, lithium, methyldopa, drugs for Parkinson's disease (e.g., levodopa and carbidopa, selegiline), paroxetine, pergolide, quinupristin-dalfopristin, rifampin.Many drugs besides haloperidol may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, quinidine, sotalol, procainamide, macrolide antibiotics (such as erythromycin), among others. Therefore, before using haloperidol, report all medications you are currently using to your doctor or pharmacist.Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with haloperidol such as: isoniazid (INH), phenothiazines (e.g., chlorpromazine, fluphenazine, thioridazine), theophylline, tramadol, or tricyclic antidepressants (e.g., amitriptyline, nortriptyline), among others. Consult your pharmacist or doctor for more information.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure medications (e.g., phenytoin, valproic acid), medicine for sleep or anxiety (alprazolam, clonazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medications (e.g., risperidone, trazodone).Check the labels on all your medicines (e.g., allergy, cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.
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