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- What is guanfacine-oral, and how does it work (mechanism of action)?
- What brand names are available for guanfacine-oral?
- Is guanfacine-oral available as a generic drug?
- Do I need a prescription for guanfacine-oral?
- What are the side effects of guanfacine-oral?
- What is the dosage for guanfacine-oral?
- Which drugs or supplements interact with guanfacine-oral?
- Is guanfacine-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about guanfacine-oral?
What is guanfacine-oral, and how does it work (mechanism of action)?
Guanfacine is an oral, centrally-acting alpha 2A adrenergic receptor agonist. It is available in two different formulations, Tenex immediate release tablets and Intuniv extended release tablets. Tenex is used alone or in combination with other medications for the treatment of hypertension (high blood pressure). Guanfacine reduces blood pressure by reducing the resistance of blood flow in the blood vessels, and by decreasing heart rate.
Intuniv (guanfacine extended release) is used alone or in combination with other medications for the treatment of attention deficit hyperactivity disorder (ADHD). The exact mechanism of action of guanfacine in ADHD is unknown. Extended release guanfacine is effective for the treatment of ADHD in children and adolescents between the ages of 6 to 17 in clinical trials lasting 8 weeks.
Guanfacine was approved by the US Food and Drug Administration (FDA) in 1986.
What brand names are available for guanfacine-oral?
Is guanfacine-oral available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for guanfacine-oral?
What are the side effects of guanfacine-oral?
The most common side effects associated with guanfacine treatment are
Other important side effects that are rare, but serious, are:
- hair loss,
- memory impairment,
- heart failure,
- skin problems,
- difficulty swallowing,
- hypersensitivity or
- heart attack,
- rebound hypertension,
- kidney failure,
- rapid heartbeat, and
- visual disturbance.
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