guanfacine (Intuniv, Tenex)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: guanfacine

BRAND NAME: Intuniv, Tenex

DRUG CLASS AND MECHANISM: Guanfacine is an oral, centrally-acting alpha 2A adrenergic receptor agonist. It is available in two different formulations, Tenex immediate release tablets and Intuniv extended release tablets. Tenex is used alone or in combination with other medications for the treatment of hypertension (high blood pressure). Guanfacine reduces blood pressure by reducing the resistance of blood flow in the blood vessels, and by decreasing heart rate.

Intuniv (guanfacine extended release) is used alone or in combination with other medications for the treatment of attention deficit hyperactivity disorder (ADHD). The exact mechanism of action of guanfacine in ADHD is unknown. Extended release guanfacine is effective for the treatment of ADHD in children and adolescents between the ages of 6 to 17 in clinical trials lasting 8 weeks.

Guanfacine was approved by the US Food and Drug Administration (FDA) in 1986.

PRESCRIBED FOR: Extended release guanfacine (Intuniv) is used alone or in combination with other medications for the treatment of ADHD. Immediate release guanfacine (Tenex) is used alone or in combination with other medications for the treatment of high blood pressure.

Medically Reviewed by a Doctor on 9/11/2015

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