guanfacine (Intuniv, Tenex)

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GENERIC NAME: guanfacine

BRAND NAME: Intuniv, Tenex

DRUG CLASS AND MECHANISM: Guanfacine is an oral, centrally-acting alpha 2A adrenergic receptor agonist. It is available in two different formulations, Tenex immediate release tablets and Intuniv extended release tablets. Tenex is used alone or in combination with other medications for the treatment of hypertension (high blood pressure). Guanfacine reduces blood pressure by reducing the resistance of blood flow in the blood vessels, and by decreasing heart rate.

Intuniv (guanfacine extended release) is used alone or in combination with other medications for the treatment of attention deficit hyperactivity disorder (ADHD). The exact mechanism of action of guanfacine in ADHD is unknown. Extended release guanfacine is effective for the treatment of ADHD in children and adolescents between the ages of 6 to 17 in clinical trials lasting 8 weeks.

Guanfacine was approved by the US Food and Drug Administration (FDA) in 1986.




  • Intuniv: Extended-Release Tablets: 1, 2, 3, and 4 mg
  • Tenex: Immediate-Release Tablets: 1 and 2 mg
Medically Reviewed by a Doctor on 4/16/2014

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