guaifenesin/codeine (Cheratussin AC, Codar GF, Dex-Tuss, Guaiatussin AC, Iophen C-NR, M-Clear)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

STORAGE: Guaifenesin and codeine liquid should be stored between 15 C to 30 C (59 F to 86 F).

DOSING:

  • Adults and children 12 years of age and older: Take 2 teaspoon (10 ml) by mouth every 4 hours as needed.
  • Children 6 years to 12 years of age: Take 1 teaspoon (5 ml) by mouth every 4 hours as needed.
  • Children 2 years to 6 years of age: Consult a doctor.
  • Children under 2 years of age: Do not use.
  • Do not use more than 6 doses in a 24-hour period.

DRUG INTERACTIONS: Naltrexone (Riva) decreases the effect of codeine in the body, therefore codeine must not be used with naltrexone.

Any other medications that increase drowsiness should be used with caution with guaifenesin and codeine.

PREGNANCY: There are no adequate studies with guaifenesin and codeine to determine its safety and effectiveness in pregnant women.

NURSING MOTHERS: Guaifenesin with codeine is excreted in breast milk; therefore, it must be used with caution in nursing mothers.

REFERENCES:

FDA Prescribing Information.

Medically Reviewed by a Doctor on 5/19/2015
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