guaifenesin and phenylephrine, Sudafed PE Non-Drying Sinus Caplets, (Entex, discontinued)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: guaifenesin and phenylephrine

BRAND NAME: Sudafed PE Non-Drying Sinus Caplets, (Entex, discontinued)

DRUG CLASS AND MECHANISM: Guaifenesin/phenylephrine is a medication that contains two different drugs, an expectorant (guaifenesin) and a decongestant (phenylephrine). The expectorant effects of guaifenesin promote drainage of mucus from the lungs by thinning the mucus. It also lubricates the irritated respiratory tract. Phenylephrine relieves stuffy nose by constricting blood vessels in the nasal air passages. This reduces the flow of fluid out of the blood vessels and into the tissues of the air passages.

PRESCRIPTION: No

GENERIC AVAILABLE: yes

PREPARATIONS: Caplet: 5 mg/200 mg

STORAGE: Store at room temperature below 30 C (86 F).

PRESCRIBED FOR: Guaifenesin/phenylephrine is used for the temporary relief of runny nose, sneezing, nasal congestion from the common cold, sinusitis, bronchitis, or sore throat.

DOSING: Guaifenesin/phenylephrine may be taken with or without food. It must be used cautiously in patients with heart (coronary artery) disease and angina, and diabetes.

DRUG INTERACTIONS: Guaifenesin/phenylephrine should not be taken with MAO inhibitors drugs due to the increased risk of serious adverse effects

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