PREGNANCY AND BREASTFEEDING SAFETY: Although one analysis found a correlation between guaifenesin use in the first trimester of pregnancy and an increased risk of hernia in the fetus, others found no increased risk of fetal malformations. Thus, guaifenesin should be used in pregnancy only if the physician feels that the potential benefits outweigh the potential and unknown risks.
It is not known if guaifenesin is secreted into breast milk.
STORAGE: Tablets, capsules, and syrup should be stored below 30 C (86 F). The liquid should not be refrigerated.
DOSAGE: Guaifenesin may be taken with or without food. The tablets should be taken whole and should not be crushed, chewed, or broken. The recommended dose is 600-1200 every 12h hours up to a maximum of 2.4 g per day. Patients should consult a health care professional if symptoms last more than 7 days.
How does guaifenesin work?: Guaifenesin is an expectorant, that is, a medication that promotes elimination of mucus from the lungs. The expectorant effects of guaifenesin promote elimination of mucous by thinning the mucous and lubricating the irritated respiratory tract. Guaifenesin is an ingredient in many over-the-counter cough and cold products. Guaifenesin was first approved by the FDA in 1952.
Reference: FDA Prescribing Information
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