guaifenesin, Humibid, Humibid LA, Robitussin, Organidin NR, Fenesin, Mucosa, Mucus Relief, Mucinex

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: guaifenesin

BRAND NAME: Humibid, Humibid LA, Robitussin, Organidin NR, Fenesin, Mucinex, Mucosa, Mucus Relief, Mucus ER

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

USES: Guaifenesin is used for the treatment of cough associated with colds and minor upper respiratory tract infections in individuals 12 years and older.

SIDE EFFECTS: Side effects of guaifenesin are uncommon, but can include:

PREPARATIONS: Tablet (extended release): 600, and 1200 mg

DRUG INTERACTIONS: There are no known drug interactions with guaifenesin.

PREGNANCY AND BREASTFEEDING SAFETY: Although one analysis found a correlation between guaifenesin use in the first trimester of pregnancy and an increased risk of hernia in the fetus, others found no increased risk of fetal malformations. Thus, guaifenesin should be used in pregnancy only if the physician feels that the potential benefits outweigh the potential and unknown risks.

It is not known if guaifenesin is secreted into breast milk.

STORAGE: Tablets, capsules, and syrup should be stored below 30 C (86 F). The liquid should not be refrigerated.

DOSING: Guaifenesin may be taken with or without food. The tablets should be taken whole and should not be crushed, chewed, or broken. The recommended dose is 600-1200 every 12h hours up to a maximum of 2.4 g per day. Patients should consult a health care professional if symptoms last more than 7 days.

DRUG CLASS AND MECHANISM: Guaifenesin is an expectorant, that is, a medication that promotes elimination of mucus from the lungs. The expectorant effects of guaifenesin promote elimination of mucous by thinning the mucous and lubricating the irritated respiratory tract. Guaifenesin is an ingredient in many over-the-counter cough and cold products. Guaifenesin was first approved by the FDA in 1952.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 1/15/2016

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