griseofulvin (Gris-Peg, Grifulvin V, Griseofulvin Ultramicrosize)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: griseofulvin

BRAND NAME: Gris-Peg, Grifulvin V, Griseofulvin Ultramicrosize

DISCONTINUED BRANDS: Fulvicin P/G, Fulvicin U/F, Grisactin, Grisactin Ultra, Ultragris

DRUG CLASS AND MECHANISM: Griseofulvin is an oral antibiotic that is used to treat fungal infections of the skin, body, hair/beard, or nails. Griseofulvin prevents fungal cells from dividing and multiplying. Griseofulvin also is deposited in keratin cells on the surface of the skin making it difficult for fungus to invade the skin and other tissues. Griseofulvin is effective against Microsporum, Epidermophyton and Trichophyton. It is not effective against bacteria. The FDA approved griseofulvin in 1959.

PRESCRIBED FOR: Griseofulvin is used to treat fungal infections including:

SIDE EFFECTS WARNING:

  • Severe skin reactions including Steven-Johnson syndrome and toxic epidermal necrolysis have been reported following griseofulvin use. These reactions are serious and can result in hospitalization or death.
  • Liver injury has been reported with use of griseofulvin. Elevations in liver enzymes (AST and ALT), bilirubin and jaundice have been reported. These reactions may be serious and may result in hospitalization or death.

SIDE EFFECTS:

Reported side effects include:

Medically Reviewed by a Doctor on 10/14/2015

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