DRUG INTERACTIONS: Drug interaction studies have not been conducted with granisetron. Granisetron is broken down in the body by cytochrome P-450 liver enzymes. Drugs that increase (for example, phenobarbital) or decrease (for example, ketoconazole [Nizoral, Extina, Xolegel, Kuric]) the activity of cytochrome P-450 liver enzymes may affect the levels of granisetron in the body.
PREGNANCY: There are no adequate studies of granisetron use in pregnant women. It should only be used during pregnancy if its need outweighs the unknown risks.
Allergic reactions may occur rarely.
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