granisetron transdermal system (patch), Sancuso

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Medical and Pharmacy Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Cancer 101: Cancer Explained

DRUG INTERACTIONS: Drug interaction studies have not been conducted with granisetron. Granisetron is broken down in the body by cytochrome P-450 liver enzymes. Drugs that increase (for example, phenobarbital) or decrease (for example, ketoconazole [Nizoral, Extina, Xolegel, Kuric]) the activity of cytochrome P-450 liver enzymes may affect the levels of granisetron in the body.

PREGNANCY: There are no adequate studies of granisetron use in pregnant women. It should only be used during pregnancy if its need outweighs the unknown risks.

NURSING MOTHERS: It is not known whether granisetron is excreted in breast milk. Nursing mothers should consider not breastfeeding.

SIDE EFFECTS: The most common adverse effects of granisetron are constipation and headache. Other adverse effects include anxiety, dizziness, diarrhea, abdominal pain, and chest pain.

Allergic reactions may occur rarely.

Medically Reviewed by a Doctor on 8/1/2014

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