Escherichia coli (E. coli) from binding to urinary tract walls. Berberine also has properties that can lower blood pressure and improve irregular heartbeats. In addition, early research suggests that berberine can lower blood sugar and "bad" low-density lipoprotein (LDL) cholesterol.
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Many of the important chemicals in goldenseal are poorly absorbed when taken by mouth and might not reach the concentrations needed to have significant effects in humans. So, it is unknown whether goldenseal has the same benefits as berberine.
Special Precautions & Warnings:Pregnancy and breast-feeding: Using goldenseal during pregnancy or breast-feeding is LIKELY UNSAFE for the infant. A hazardous chemical in goldenseal can cross the placenta and can also find its way into breast milk. Brain damage (kernicterus) has developed in newborn infants exposed to goldenseal. Do not use goldenseal during pregnancy or breast-feeding.
Children: Don't use goldenseal in newborn babies. It is LIKELY UNSAFE for them. It might cause brain damage (kernicterus).
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