glycopyrrolate (Robinul, Robinul Forte, Cuvposa, Glycate) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

This drug should not be used in patients with glaucoma.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Glycopyrrolate injection is available in 0.2 mg/ml strength in 1 ml and 2 ml single-use vials. It is also available in 5 ml and 20 ml multi-use vials. All vials contain benzyl alcohol 0.9% as preservative.

STORAGE: Store Glycopyrrolate injection at room temperature between 20 C and 25 C (68 F and 77 F).

DOSING:

Adults

  • Preanesthetic medication: Inject 0.004 mg/kg intramuscularly or intravenously 30 to 60 minutes prior to surgery.
  • Intraoperative medication: Inject 0.1 mg as a single dose intravenously every 2 to 3 minutes as needed.
  • Reversal of neuromuscular blockade: Inject 0.2 mg for each 1 mg of neostigmine or 5 mg of pyridostigmine given.
  • Peptic ulcer: Inject 0.1 mg intramuscularly or intravenously at 4-hour intervals, up to 3 to 4 times daily. May increase to 0.2 mg if needed.

Children

  • Preanesthetic medication (children over 2 years of age): Inject 0.004 mg/kg intramuscularly, given 30 to 60 minutes prior to anesthesia, narcotic, or sedative.
  • Preanesthetic medication (Infants of 1 month to 2 years of age): Inject up to 0.009 mg/kg.
  • Intraoperative medication: Inject 0.004 mg/kg as single dose intravenously every 2 to 3 minutes as needed. Do not exceed 0.1 mg in a single dose.
  • Reversal of neuromuscular blockade: Inject 0.2 mg for each 1 mg of neostigmine or 5 mg of pyridostigmine given.

Glycopyrrolate Injection is not recommended for the treatment of peptic ulcer in pediatric patients.

DRUG INTERACTIONS: Glycopyrrolate should not be used with anti-cholinergic drugs such as phenothiazines, Parkinson's drugs, or tricyclic antidepressants because it can significantly increase anticholinergic side effects like mydriasis (pupil dilation), high blood pressure (hypertension), flushing, fever, and increased heart rate.

Medically Reviewed by a Doctor on 10/7/2015


Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index

Health Solutions From Our Sponsors