glycopyrrolate (Robinul, Robinul Forte, Cuvposa, Glycate) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Glycopyrrolate Injection is not recommended for the treatment of peptic ulcer in pediatric patients.

DRUG INTERACTIONS: Glycopyrrolate should not be used with anti-cholinergic drugs such as phenothiazines, Parkinson's drugs, or tricyclic antidepressants because it can significantly increase anticholinergic side effects like mydriasis (pupil dilation), high blood pressure (hypertension), flushing, fever, and increased heart rate.

Glycopyrrolate should be used with caution with potassium chloride because concomitant use can decrease bowel movement and can cause irritation or lesions in the stomach and intestine.

PREGNANCY: There are no adequate studies done on glycopyrrolate to determine safe and effective use in pregnant women. It has been shown that small amounts of glycopyrrolate will pass the placental barrier.

NURSING MOTHERS: It is not known whether glycopyrrolate enters breast milk; therefore, it is best to be cautious before using it in nursing mothers. Anticholinergics may cause suppression of lactation.

SIDE EFFECTS: Side effects of glycopyrrolate are dry mouth, urinary retention, blurred vision, dilated pupils, increased heart rate, sweating, weakness, dizziness, dry skin, constipation, urinary retention and mental confusion. This drug should not be used in patients with glaucoma.

REFERENCE: FDA Prescribing Information.


Medically Reviewed by a Doctor on 6/27/2014


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