glycerin (Fleet Suppository, Pedia-Lax Suppository, Colace Suppository)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

woman with abdominal pain

GENERIC NAME: glycerin

BRAND NAME: Fleet Suppository, Pedia-Lax Suppository, Colace Suppository

DRUG CLASS AND MECHANISM: Glycerin suppositories are hyperosmotic laxatives. Glycerin suppositories work by increasing water volume in intestines and softening stool, causing the intestines to contract and produce bowel movements.

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Adult glycerin rectal suppositories are available in 2 gram strengths in packages of 12 suppositories.
  • Pediatric glycerin rectal suppositories are available in 1 gram strengths in packages of 12 suppositories.

STORAGE: Store glycerin suppositories between temperatures 15 C and 30 C (59 F and 86 F).

PRESCRIBED FOR: Glycerin suppositories are used for occasional relief of constipation.

DOSING:

  • Adults and children of age 6 and older: Insert one 2 g suppository rectally and retain for about 15 minutes or as directed by a doctor.
  • Children of age 2 to under 6: Insert one 1 g suppository rectally, or as directed by doctor.
  • Safe and effective use of glycerin rectal suppositories is not established for children under 2 years of age.

DRUG INTERACTIONS: No drug interactions have been established with glycerin rectal suppositories.

PREGNANCY: There are no adequate studies done on glycerin rectal suppositories to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether glycerin enters breast milk. It is most likely compatible with breastfeeding.

SIDE EFFECTS: Side effects of glycerin rectal suppositories are rectal discomfort, burning sensation, diarrhea and nausea.

REFERENCE: NIH. ADULT GLYCERIN LAXATIVE - glycerin syppository.

Medically Reviewed by a Doctor on 10/2/2014

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