Glucovance (glyburide/metformin)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Is glyburide/metformin tablets-oral safe to take if I'm pregnant or breastfeeding?

:

  • Glucovance has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, Glucovance should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Glucovance is classified as FDA pregnancy risk category B.
  • It is not known if Glucovance is excreted in breast milk. Due to the lack of safety data and the potential risk for hypoglycemia (low blood glucose) in nursing infants, use of Glucovance in nursing mothers is not recommended.

What else should I know about glyburide/metformin tablets-oral?

What preparations of glyburide/metformin tablets-oral are available?

Oral tablets: 1.25/250, 2.5/500, and 5/500 mg

How should I keep glyburide/metformin tablets-oral stored?

  • Tablets should be stored at room temperature, between 15 C and 30 C (59 F to 86 F).
  • Tablets should be dispensed and stored in an air- tight, light resistance container.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 8/31/2016

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