Glutathione

What other names is Glutathione known by?

Gamma-Glutamylcysteinylglycine, Gamma-L-Glutamyl-L-Cysteinylglycine, Gamma-L-Glutamyl-L-Cystéinylglycine, Glutathion, Glutatión, L-Gamma-Glutamyl-L-Cysteinyl-Glycine, L-Gamma-Glutamyl-L-Cystéinyl-Glycine, L-Glutathion, L-Glutathione, GSH, N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine.

What is Glutathione?

Glutathione is a substance produced naturally by the liver. It is also found in fruits, vegetables, and meats.

People take glutathione by mouth for treating cataracts and glaucoma, preventing aging, treating or preventing alcoholism, asthma, cancer, heart disease (atherosclerosis and high cholesterol), hepatitis, liver disease, diseases that weaken the body's defense system (including AIDS and chronic fatigue syndrome), memory loss, Alzheimer's disease, osteoarthritis, and Parkinson's disease. Glutathione is also used for maintaining the body's defense system (immune system) and fighting metal and drug poisoning.

Glutathione is breathed in (inhaled) for treating lung diseases, including idiopathic pulmonary fibrosis, cystic fibrosis, and lung disease in people with HIV disease.

Healthcare providers give glutathione as a shot (by injection into the muscle) for preventing poisonous side effects of cancer treatment (chemotherapy) and for treating the inability to father a child (male infertility).

Healthcare providers also give glutathione intravenously (by injection into the vein, by IV) for preventing "tired blood" (anemia) in kidney patients undergoing hemodialysis treatment, preventing kidney problems after heart bypass surgery, treating Parkinson's disease, improving blood flow and decreasing clotting in individuals with "hardening of the arteries" (atherosclerosis), treating diabetes, and preventing toxic side effects of chemotherapy.

Possibly Effective for...



INTRAVENOUS
  • Reducing side effects of chemotherapy treatments for cancer.

Insufficient Evidence to Rate Effectiveness for...



TAKEN BY MOUTH
INHALED
  • Treating lung diseases.
  • Other conditions.
INTRAVENOUS
  • Treating Parkinson's disease.
  • Diabetes.
  • Anemia in people on hemodialysis.
  • "Hardening of the arteries" (atherosclerosis).
  • Infertility in men.
  • Other conditions.
More evidence is needed to rate glutathione for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).


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