Glucosamine Hydrochloride and N-Acetyl Glucosamine are different than Glucosamine Sulfate. For information on these different products, see the Glucosamine Hydrochloride and N-Acetyl Glucosamine listings.
Don't confuse glucosamine sulfate with other forms such as glucosamine hydrochloride or N-acetyl-glucosamine. They may not have the same effects.
osteoarthritis. It seems to work about as well as some nonprescription pain medications. But glucosamine takes about twice as long to work, four weeks instead of two. There is some evidence that glucosamine sulfate may actually keep the joint problems from getting worse. Other pain relievers can reduce the pain but do not prevent the disease from slowly destroying more of the joint. Glucosamine sulfate might not be as effective for reducing pain in more severe, long-standing osteoarthritis.
Glucosamine sulfate is often marketed in combination products that also contain chondroitin sulfate. So far, there is no evidence that the combination products work any better than glucosamine sulfate or chondroitin sulfate alone. Buying a combination product is probably not worth the extra cost.
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Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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